Category: Current Issue

Research progress of intracameral moxifloxacin in the prevention of bacterial endophthalmitis after cataract surgery

Authors: Yan Weijia,  Zhou Haiyan,  Yan Hong DOI: 10.3760/cma.j.cn115989-20210304-00146 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 461-465. Abstract Postoperative endophthalmitis (POE) is a serious vision-threatening complication of cataract surgery, with an incidence rate of 0.033%-0.11% in China.In recent years, numerous retrospective studies and data analyses have reported that intracameral injection of antibiotics can […]

Advances in intraocular lens power calculation formulas in high myopia

Authors: Zhang Chi,  Ye Zi,  Li Zhaohui DOI: 10.3760/cma.j.cn115989-20200512-00341 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 466-469. Abstract As the number of cataract patients with high myopia increases, and the cataract surgery shifts from a rehabilitation procedure to a refractive procedure, achieving a good postoperative visual acuity has been the target of cataract […]

Biomarkers in ocular chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Authors: Wang Chunmiao,  Zhang Qi DOI: 10.3760/cma.j.cn115989-20190121-00025 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 470-474. Abstract Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a common treatment for hematological malignant and non-malignant diseases.However, dry eye, ocular chronic graft-versus-host disease (cGVHD) and other common ocular complications related to cGVHD after allo-HSCT, can seriously affect the […]

Research progress of correlation between microRNA and the pathogenesis of cataract

Authors: Pu Yadi,  Li Yuanbin DOI: 10.3760/cma.j.cn115989-20200413-00255 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 475-480. Abstract MicroRNA (miRNA) is a kind of small non-coding RNA, which can specifically bind to the 3′ untranslated region of the target RNA, inducing the degradation or inhibiting the translation of the target mRNA, and ultimately affecting the […]

Advance in mechanism and management study of vernal keratoconjunctivitis

Authors: Li Suxia,  Shi Weiyun DOI: 10.3760/cma.j.cn115989-20220413-00159 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 481-486. Abstract Vernal keratoconjunctivitis (VKC) is a chronic, bilateral allergic conjunctivitis common in school children.VKC is classified into palpebral-conjunctival type, limbal type and mixed type primarily based on clinical findings.Most allergic conjunctivitis does not impair vision, however, VKC probably […]

New paradigms of immune regulation in glaucoma during the whole clinical process

Authors: Wu Jian,  Su Wenru,  Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20220314-00104 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 289-293. Abstract Glaucoma is an irreversible blinding eye disease caused by the structural and functional damage of optic nerve induced by pathological increase of intraocular pressure (IOP), characterized by multiple causes and strong heterogeneity.The control of IOP […]

Inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts

Authors: Wu Sharengaowa,  Cui Renzhe,  Lu Di,  Ding Haoxuan,  Sun Lixia DOI: 10.3760/cma.j.cn115989-20200609-00410 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 294-302. Abstract Objective To investigate the inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts (HConF). Methods HConF were divided into blank control group, lipofectamine 2000 (Lipo2000) group, […]

Specific expression of transmembrane protein 26 in retina and its association with primary open-angle glaucoma

Authors: Yin Yi,  Mao Yao,  Yang Zhenglin,  Huang Lulin DOI: 10.3760/cma.j.cn115989-20200112-00021 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 303-309. Abstract Objective To predict the transmembrane structure of transmembrane protein 26 (TMEM26), observe its expression in human retina and mouse retina, and investigate the relationship between it and primary open-angle glaucoma (POAG). Methods The […]

Inhibitory effect of necrostatin-1 on necroptosis of retinal ganglion cells in rats with acute ocular hypertension

Authors: Jing Yuanyuan,  Ma Yi,  Wang Kai,  Liu Zhuqing DOI: 10.3760/cma.j.cn115989-20191108-00488 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 310-315. Abstract Objective To investigate the inhibitory effect of specific inhibitor of necroptosis necrostatin-1 (Nec-1) on necroptosis of retinal ganglion cells (RGCs) in rats with acute ocular hypertension. Methods Twenty-four adult male Sprague Dawley rats […]

Inhibitory effect of ILK-siRNA-AAV on scar formation after glaucoma filtering surgery in rats

Authors: Xing Yao,  Wang Jianming,  Fan Yazhi,  Xiong Lei,  Wang Wenjing,  Cui Lijun DOI: 10.3760/cma.j.cn115989-20210617-00362 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 316-325. Abstract Objective To investigate the role of integrin-linked kinase (ILK)-small interfering RNA (siRNA)-adeno-associated virus (AAV) in scar formation after glaucoma filtering surgery in rat eyes. Methods Forty-eight Sprague Dawley rats […]