Authors: Du Man, Zhang Li, Li Peng, Qi Hongmei, Lu Xiuhai DOI: 10.3760/cma.j.cn115989-20190702-00284 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 119-125. Abstract [View PDF] [Read Full Text] Objective To compare the effect of fluorescence staining and periodic acid-Schiff staining in the diagnosis of […]
Category: Experimental Science
Safety of intravitreal injection of recombinant human endostatin in rabbits
Authors: Xia Ying, Chen Fang, Du Wei, Zhu Jun, Jia Shuya, Ma Haiying, Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20201104-00744 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 1-6. Abstract [View PDF] [Read Full Text] Objective […]
Protective effect of Radix Astragali seu Hedysari compound on rat retinal DNA damage induced by acute hypobaric hypoxia
Authors: Li Yanrong, Xin Xiaorong DOI: 10.3760/cma.j.cn115989-20190903-00380 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 7-12. Abstract [View PDF] [Read Full Text] Objective To investigate the rat retinal DNA damage induced by acute hypobaric hypoxia and the protective effect of […]
Promotion effect of miR-155 on transforming growth factor β2-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells
Authors: Wang Yanting, Jin Xuemin, Li Xiaohua, Zhao Zhaoxia DOI: 10.3760/cma.j.cn115989-20200309-00158 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 13-19. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of microRNA-155(miR-155) on transforming growth factor β2 (TGF-β2)-induced epithelial-mesenchymal transition of human retinal […]
Preparation and drug release effect evaluation of drug-loaded cross-linked decellularized corneal stromal lenticules in vitro
Authors: Rao Jing, Chen Jiansu, Gu Jianing, Chen Xiao, Wang Yini, Liu Yonghuan, Pu Aijun, Zhou Qizhi DOI: 10.3760/cma.j.cn115989-20190817-00353 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1004-1010. Abstract [View PDF] [Read Full Text] Objective To prepare a drug release system of drug-loaded cross-linked […]
Network pharmacology analysis of metformin against diabetic retinopathy
Authors: Chen Yuan, Xing Qian, Huang Zhengru DOI: 10.3760/cma.j.cn115989-20191215-00543 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1011-1015. Abstract [View PDF] [Read Full Text] Objective To explore the pharmacological molecular mechanisms of metformin against diabetic retinopathy (DR) based on network pharmacology approach. Methods After […]
Anti-apoptosis and anti-inflammation effects and mechanism of berberine on high-concentration glucose induced rat retinal Müller cells
Authors: Jin Yiping, Zhu Haohao, Liao Yujie, Yu Xiaoyan DOI: 10.3760/cma.j.cn115989-20200917-00647 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1016-1024. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of berberine on Sprague Dawley (SD) rat retinal Müller cells cultured by high […]
Protective effect and mechanism of esculetin on oxidative damaged ARPE-19 cells
Authors: Zhang Yingjun, Bai Ge, He Xiangdong, Zhang Donglei, He Wei DOI: 10.3760/cma.j.cn115989-20200224-00101 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1025-1031. Abstract [View PDF] [Read Full Text] Objective To study the protective effect and the mechanism of esculetin on oxidative-stressed human retinal pigment […]
Ocular pharmacokinetics of econazole solid lipid nanoparticle eye drops after single dose topical administration in rabbits
Authors: Liang Zhen, Zhang Zhen, Li Jingguo, Yang Jingjing, Lu Ping, Zhou Tianyang, Zhang Junjie DOI: 10.3760/cma.j.cn115989-20191008-00429 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1032-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the pharmacokinetics of econazole solid lipid nanoparticles (E-SLNs) after […]
Ocular pharmacokinetics of topical administration of butenafine nanomicelles in rabbit eyes
Authors: Lu Ping, Liang Zhen, Zhang Zhen, Yang Jingjing, Song Fei, Li Jingguo, Zhou Tianyang, Zhang Junjie DOI: 10.3760/cma.j.cn115989-20200526-00374 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1038-1044. Abstract [View PDF] [Read Full Text] Objective To study the pharmacokinetics of the broad-spectrum antifungal drug […]