Authors: Li Guo, Chen Ying, Yan Hong, Zhou Xiyuan DOI: 10.3760/cma.j.cn115989-20200730-00546 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 382-387. Abstract [View PDF] [Read Full Text] Objective To study the protein leakage of mouse lens treated with hydrogen peroxide in vitro, and to identify […]
Category: Experimental Science
Construction of Crx-iCreERT2 fluorescent reporter human embryonic stem cells by CRISPR/Cas9 technology and 3D retinal organoid culture
Authors: Du Yuxin, Liu Yizong, Yan Feiyue, Shen Yin DOI: 10.3760/cma.j.cn115989-20210208-00103 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 388-397. Abstract [View PDF] [Read Full Text] Objective To establish Crx-iCreERT2 fluorescent reporter human embryonic stem cell lines using CRISPR/Cas9 technology and 3D retinal organoid […]
Inhibitory effect of miR-146a on high glucose-induced apoptosis of retinal microvascular endothelial cells and its mechanism
Authors: Gao Fei, Wu Zhipeng, Ruan Yihua DOI: 10.3760/cma.j.cn115989-20190703-00286 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 398-403. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of microRNA-146a (miR-146a) on apoptosis of human retinal microvascular endothelial cells (HRMECs) induced by high […]
Anti-oxidative stress effects of miR-125b on lens epithelial cells and its mechanism
Authors: Li Xiang, Zhang Ying, Huang Yalin, Wu Zhong, Guo Haoyi DOI: 10.3760/cma.j.cn115989-20191022-00458 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 280-288. Abstract [View PDF] [Read Full Text] Objective To investigate the anti-oxidative stress effects of microRNA 125b (miR-125b) on lens epithelial cells (LECs) […]
Inhibitory effect of siRNA-YAP1 on transforming growth factor β2-induced epithelial-mesenchymal transition in human lens epithelial cells
Authors: Zheng Liu, Hu Chao, Yang Binbin, Yang Xinggang, Ding Zhixiang DOI: 10.3760/cma.j.cn115989-20191016-00447 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 289-296. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of small interfering RNA-Yes-associated protein 1 (siRNA-YAP1) on epithelial-mesenchymal transition […]
Regulatory effect of glucocorticoid on the biological function of lens epithelial cells: a bioinformatics analysis
Authors: Yan Chufan, Han Xiao, Zhang Jinsong DOI: 10.3760/cma.j.cn115989-20190821-00359 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 297-303. Abstract [View PDF] [Read Full Text] Objective To analyze the effect of glucocorticoid on the biological function of lens epithelial cells (LECs) by bioinformatics and predict […]
Evaluation of eye injury degree of laser irradiation frequency and single duration
Authors: Zhang Yufei, Wei Dongyu, Wang Wei, Liu Daming, Ren Ze, Li Xiangqian, Chen Tao, Zhang Zuoming DOI: 10.3760/cma.j.cn115989-20200105-00007 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 184-190. Abstract [View PDF] [Read Full Text] Objective To explore the effects of laser irradiation parameters […]
Protective effect of vitexin on retinal ganglion cells in rat retinal ischemia-reperfusion injury model
Authors: Li Manli, Fan Ke, Cui Hongpei DOI: 10.3760/cma.j.cn115989-20200509-00319 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 191-197. Abstract [View PDF] [Read Full Text] Objective To explore the protective effect of vitexin on retinal ganglion stem cells (RGCs) from oxidative stress caused by […]
Repair effect of platelet-rich plasma on traumatic optic nerve injury in rabbits and its mechanism
Authors: Li Linling, Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200701-00468 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 198-206. Abstract [View PDF] [Read Full Text] Objective To study the therapeutic effect and mechanism of autologous platelet-rich plasma (PRP) on rabbit traumatic optic neuropathies (TON) and retina. […]
Inhibitory effects of lncRNA ADPGK-AS1 on the biological behaviours of human retinoblastoma cells and its regulating mechanism
Authors: Zhang Jun, Liu Cailin, Bu Zhanyun DOI: 10.3760/cma.j.cn115989-20200819-00599 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 207-215. Abstract [View PDF] [Read Full Text] Objective To explore the effects of long noncoding RNA adenosine diphosphate-dependent glucokinase antisense RNA 1(ADPGK-AS1) […]