Category: 2021, No. 06

Chinese experts consensus on standardized construction of dry eye clinical center

Author: Chinese Experts Consensus Members on Standardized Construction of Dry Eye Clinical Center,  Dry Eye Rehabilitation Specialty, Visual Rehabilitation Committee of Chinese Rehabilitation Medicine Association DOI: 10.3760/cma.j.cn115989-20210223-00128 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 473-476. Abstract In recent years, more and more attention has been paid to the dry eye clinical center in […]

Inhibiting effect of retinal Sigma-1 receptor antagonist on the form deprivation myopia in guinea pigs and its mechanism

Authors: Chen Yuanyuan,  Xie Fujuan,  Li Haibo,  Guan Yuxin,  Mao Junfeng DOI: 10.3760/cma.j.cn115989-20200615-00433 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 477-482. Abstract Objective To investigate the role and mechanism of retinal Sigma-1 receptor antagonist N, N-diethyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethanaminehydrochloride (NE-100) in the formation of form deprivation myopia (FDM) in guinea pigs. Methods Eighty-five 21-day-old guinea pigs […]

Relationship between irradiation time of riboflavin-ultraviolet A scleral collagen cross-linking and retinal injury

Authors: Yan Dong,  Liu Limei,  Ming Chunxiu,  Zhang Shaobin DOI: 10.3760/cma.j.cn115989-20190703-00287 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 483-489. Abstract Objective To investigate the effects of riboflavin-ultraviolet A scleral collagen cross-linking on the retina under different irradiation time, and to determine the safe irradiation time. Methods Sixty healthy New Zealand white rabbits were […]

All-trans retinoic acid-induced apoptosis signaling pathway in ARPE-19 cells

Authors: Wu Juan,  Cui Dongmei,  Yang Xiao,  Zeng Junwen DOI: 10.3760/cma.j.cn115989-20190704-00293 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 490-497. Abstract Objective To investigate all-trans retinoic acid(ATRA)-induced apoptosis signaling pathway in ARPE-19 cells in vitro. Methods The APRE-19 cell was treated with different concentrations of ATRA for 24 hours and 48 hours.Cell counting kit-8 […]

Label-free quantitative proteomic analysis of aqueous humor in patients with high myopia

Authors: Xue Min,  Ren Xinjun,  Ke Yifeng,  Liu Juping,  Fan Xiaoe,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200716-00503 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 498-504. Abstract Objective To characterize proteomic profile in aqueous humor of patients with high myopia using quantitative proteomic analysis. Methods Sixty-eight age-related cataract patients were divided into high myopic cataract group […]

Transcriptomics analysis of hypoxia-induced retinal pigment epithelium cell injury

Authors: Lu Cong,  Shi Pingling,  Yang Qixiang,  Song Hao,  Li Miao,  Zhang Beibei,  Song Zongming DOI: 10.3760/cma.j.cn115989-20201127-00799 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 505-514. Abstract Objective To analyze differentially expressed genes (DEGs) and the changes of signal pathways in human retinal pigment epithelium cells (ARPE-19) under hypoxic and normoxic conditions and to […]

Comparison of modulation transfer function between the eyes after small-incision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis

Authors: Cui Tong,  Wang Yan,  Zhang Lin,  Cheng Wenbo,  Zhao Wei DOI: 10.3760/cma.j.cn115989-20210310-00159 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 515-521. Abstract Objective To investigate and compare the changes of modulation transfer function (MTF) after small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis(FS-LASIK). Methods A cohort study was conducted.One hundred […]

Changes of corneal anterior surface morphology and higher-order aberrations after Smart

Authors: Wang Shuhan,  Wang Guiqin,  Yu Aomiao,  Zhao Shaozhen,  Wei Ruihua,  Huang Yue DOI: 10.3760/cma.j.cn115989-20191119-00501 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 522-527. Abstract Objective To compare the changes of corneal asphericity and higher-order aberrations after smart pulse technology-assisted transepithelial photorefractive keratectomy (Smart) for low and moderate myopia and to investigate the changes […]

Imaging etiology of pathological myopia results in visual impairment

Authors: Chen Yanru,  Li Xiaoxin,  Li Minghan DOI: 10.3760/cma.j.cn115989-20190321-00127 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 528-533. Abstract Objective To analyze the imaging etiology of patients having vision loss with pathological myopia. Methods A cross-sectional study was conducted.The clinical data of 110 cases (138 eyes) who had vision loss with pathological myopia diagnosed […]

Comparison of distance visual acuity measurement between dynamic optotype and LogMAR E charts

Authors: Rita WM Sum,  George C Woo DOI: 10.3760/cma.j.cn115989-20200613-00431 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 534-537. Abstract Objective To investigate if the dynamic optotype is comparable with conventional logarithm of the minimum angle of resolution (LogMAR) optotype. Methods This is a cross-sectional study investigating visual acuity measurement with two methods.The study lasted […]