Category: Experimental Science

Evaluation of the retinal differentiation ability of human induced pluripotent stem cells reprogrammed from different somatic cells

Authors: Xie Bingbing,  Guan Yuanyuan,  Gao Guanjie,  Zheng Dandan,  Xu Ping,  Song Xiaojing,  Zhong Xiufeng DOI: 10.3760/cma.j.cn115989-20200805-00563 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 821-827. Abstract                              [View PDF] [Read Full Text] Objective To evaluate the retinal differentiation ability of human induced pluripotent stem […]

Transplantation of retinal organoids in vivo and long-term survival of photoreceptor cells

Authors: Sun Xiao,  Xie Haohuan,  Zhang Mei,  Xue Tian DOI: 10.3760/cma.j.cn.115989-20200331-00227 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 829-836. Abstract                               [View PDF] [Read Full Text] Objective To investigate the differentiation process of human-induced pluripotent stem cells (hiPSCs) into retinal organoids (ROs) in vitro […]

Differentially expressed genes analysis on the role of Wnt5a in lentoid body induction from human embryonic stem cells

Authors: Chen Yijia,  Li Jinyan,  Ouyang Shuai,  Luo Lixia DOI: 10.3760/cma.j.cn115989-20200308-00156 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 837-844. Abstract                               [View PDF] [Read Full Text] Objective To investigate the mechanism of Wnt5a in lentoid body (LB) induction from human embryonic stem cells (hESCs). […]

Inhibitory effects of miR-146a on retinal inflammation induced by high glucose in human retinal endothelial cells

Authors: Gu Shun,  Zhan Pengfei,  Wang Wenjuan,  Wang Xiaolu,  Wei Tingting,  Zhu Lingpeng,  Wang Yangningzhi,  Yin Li,  Xie Tianhua,  Yao Yong DOI: 10.3760/cma.j.cn115989-20190213-00051 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 733-739. Abstract                               [View PDF] [Read Full Text] Objective To observe the effects of […]

Effect of recombinant human vascular endostatin on retinal barrier related proteins in early diabetic rats

Authors: Zhou Jinhua,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20190228-00092 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 740-745. Abstract                              [View PDF] [Read Full Text] Objective To observe the effect of recombinant human vascular endostatin(ES) on retinal barrier related proteins in early streptozotocin […]

Application of virus tracing tools in the study of function and morphology of neurons in the visual circuit

Authors: Shen Kejiong,  Shen Yin DOI: 10.3760/cma.j.cn115989-20191021-00457 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 746-753. Abstract                               [View PDF] [Read Full Text] Objective To utilize four viral tracer tools with different properties, to visualize cell morphology and connectome in visual pathways and explore and […]

Effects of miR-338-3p/TCF4 on choroidal microvascular endothelial cell proliferation and apoptosis

Authors: Li Jiancheng,  Bu Zhanyun,  Pan Junhui DOI: 10.3760/cma.j.cn115989-20200407-00242 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 639-645. Abstract                              [View PDF] [Read Full Text] Objective To investigate whether microRNA-338-3p (miR-338-3p) affects the proliferation and apoptosis of choroidal microvascular endothelial cells by […]

Differential gene expression profiles of trabecular meshwork between POAG and non-POAG donated eyes by using RNA-sequencing

Authors: Liu Lifang,  Zeng Jinhui,  Huang Chukai,  Wang Geng,  Zhang Mingzhi DOI: 10.3760/cma.j.cn115989-20191018-00451 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 646-652. Abstract                               [View PDF] [Read Full Text] Objective To investigate gene basis of primary open angle glaucoma (POAG) by comparing gene expression profile of […]

In vitro interactions between antifungals and tacrolimus against Fusarium solani

Authors: Chen Xiaolian,  Ding Hui,  Liu Hongshan,  He Hong,  Wu Jiaochan,  Hu Xianlyu,  Zhong Xingwu DOI: 10.3760/cma.j.cn115989-20190613-00260 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 653-658. Abstract                              [View PDF] [Read Full Text] Objective To investigate the in vitro interaction between antifungals and tacrolimus against Fusarium solani. Methods According […]

Establishment and evaluation of a novel retinal ischemia-reperfusion injury model

Authors: Wen Xin,  Yuan Miner,  Li Cheng,  Zeng Jieting,  Lin Xiaofeng DOI: 10.3760/cma.j.cn115989-20190404-00162 Published 2020-07-10 Cite as Chin J Exp Ophthalmol, 2020,38(07): 566-572. Abstract                              [View PDF] [Read Full Text] Objective To explore the feasibility to establish a novel retinal ischemia reperfusion (RIR) injury model by applying […]