Category: 2021, No. 01

Safety of intravitreal injection of recombinant human endostatin in rabbits

Authors: Xia Ying,  Chen Fang,  Du Wei,  Zhu Jun,  Jia Shuya,  Ma Haiying,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20201104-00744 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 1-6. Abstract Objective To investigate and evaluate the safety of intravitreal injection of recombinant human endostatin (rh-endostatin) with different concentrations in rabbit eyes. Methods Thirty healthy adult New Zealand […]

Protective effect of Radix Astragali seu Hedysari compound on rat retinal DNA damage induced by acute hypobaric hypoxia

Authors: Li Yanrong,  Xin Xiaorong DOI: 10.3760/cma.j.cn115989-20190903-00380 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 7-12. Abstract Objective To investigate the rat retinal DNA damage induced by acute hypobaric hypoxia and the protective effect of Radix Astragali seu Hedysari compound on it. Methods Seventy-two healthy clean grade male Sprague Dawley (SD) rats were randomly […]

Promotion effect of miR-155 on transforming growth factor β2-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells

Authors: Wang Yanting,  Jin Xuemin,  Li Xiaohua,  Zhao Zhaoxia DOI: 10.3760/cma.j.cn115989-20200309-00158 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 13-19. Abstract Objective To investigate the effect of microRNA-155(miR-155) on transforming growth factor β2 (TGF-β2)-induced epithelial-mesenchymal transition of human retinal pigment epithelial cells and its mechanism. Methods The retinal pigment epithelial cell ARPE-19 cell line […]

Effect of anti-vascular endothelial growth factor therapy on wet age-related macular degeneration and its recurrence factors

Authors: Cheng Zifang,  Wang Yusheng,  Wang Haiyan,  Sun Dongjie,  Zhu Jinting,  Li Manhong DOI: 10.3760/cma.j.cn115989-20201104-00743 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 20-26. 【Read Full Text】【Download PDF】 Abstract                                                                                                                                                                                                                    Objective To evaluate the effect of anti-vascular endothelial growth factor (VEGF) in patients with wet age-related macular degeneration (wAMD) and investigate the recurrence factors. Methods […]

Change regularity of adult subfoveal choroidal thickness with age and its influencing factors

Authors: Huo Yanjiao,  Guo Yan,  Wang Huaizhou,  Li lei,  Cao Kai,  Wang Ningli DOI: 10.3760/cma.j.cn115989-20190402-00164 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 29-33. Abstract Objective To investigate the change regularity and influencing factors of subfoveal choroidal thickness (SFCT) with age among adults. Methods A cross-sectional study was adopted.A total of 281 Chinese adults, […]

Clinical features of ocular anomalies in infants with incontinentia pigmenti

Authors: Wang Liang,  Li Manhong,  Zhang Zifeng,  Yan Hongxiang,  Wu Lei,  Zhou Yi,  Fan Jing,  Gou Kaili,  Wang Yusheng DOI: 10.3760/cma.j.cn115989-20200624-00451 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 34-41. Abstract Objective To investigate the ocular clinical manifestations in pediatric patients with incontinentia pigmenti (IP). Methods A case series study was carried out and […]

Efficacy and safety of conbercept for choroidal neovascularization secondary to chronic central serous chorioretinopathy

Auhtors: Mao Jianbo,  Zhang Caiyun,  Shen Lijun,  Lao Jimeng,  Shao Yirun,  Wu Hanfei,  Chen Yiqi,  Tao Jiwei DOI: 10.3760/cma.j.cn115989-20201104-00742 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 42-46. Abstract Objective To evaluate the efficacy and safety of conbercept in patients with choroidal neovascularization secondary to chronic central serous chorioretinopathy (CSC-CNV). Methods A retrospective case […]

Effect of attenuated-dose aflibercept intravitreal injection on retinopathy of prematurity

Authors: Long Yang,  Wan Weiwei,  Liu Hongzhuo,  Wan Wencui DOI: 10.3760/cma.j.cn115989-20200705-00477 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 47-52. 【Read Full Text】  【Download PDF】 Abstract Objective To observe the effect of attenuated-dose aflibercept in the treatment of retinopathy of prematurity(ROP). Methods A non-randomized controlled study was conducted, and 76 eyes of 38 ROP […]

Evaluation of polypoidal choroidal vasculopathy with optical coherence tomography angiography

Authors: Xia Song,  Yang Jingyuan,  Zhao Xinyu,  Chen Youxin DOI: 10.3760/cma.j.cn115989-20201104-00741 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 54-58. Abstract Objective To investigate the characteristics of polypoidal lesions and abnormal branching vascular network (BVN) in patients with polypoidal choroidal vasculopathy (PCV) by optical coherence tomography angiography (OCTA). Methods A case series study was […]

Bibliometric analysis of proliferative vitreoretinopathy based on Web of Science database

Authors: Zhou Huaiyu,  Li Zhiqing,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20190805-00336 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 60-66. Abstract Objective To study the distribution of the literature and the trend of international research of proliferative vitreoretinopathy (PVR) in 10 years from 2009 to 2018. Methods Using Web of Science database of the American Institute […]