Category: Experimental Science

Iinhibitory effects of miR-200a on proliferation and migrating ability of conjunctival fibroblasts and its mechanism

Authors:Yin Xue,  Liang Ya,  Yuan Zhilan DOI: 10.3760/cma.j.issn.2095-0160.2016.12.008 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1087-1091. Abstract                              [Download PDF] [Read Full Text] Background Scarring of surgical area, the most important factor, leads to the failure of glaucoma filtering surgeries.Therefore, more and more attentions are paid to the causes […]

Inhibitory effects of α-crystallin on optic nerve astrocytes proliferation, activation and secretion stimulated by lipopolysaccharide

Authors:Liu Xiao,  Shao Weiyang,  Gu Xianliang,  Wang Yi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.007 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1082-1086. Abstract                              [Download PDF] [Read Full Text] Background Glial scaring induced by the activation and proliferation of astrocytes after optical nerve damage is one of causes of neural axons difficult to regeneration.Researches […]

Application of modified retinal flatmount combined with immunofluorescence staining in oxygen-induced retinopathy model

Authors:Li Rong,  Yao Guomin,  Wang Xiaodi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.005 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1077-1080. Abstract                              [Download PDF] [Read Full Text] Background Retinal flatmount of oxygen-induced retinopathy (OIR) animal models is a useful tool in the study of ischemic retinopathy.The retinas of OIR of rat or mouse […]

α-Melanocyte-stimulating hormone inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy

Authors:Yang Qianhui,  Zhang Yan,  Bo Qiyu,  Cao Yunshan,  Yang Wei,  Wang Fei,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2016.12.004 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1072-1076. Abstract                               [Download PDF] [Read Full Text] Background Retinal neovascularization (RNV) occurs in multiple eye diseases, which can lead to bleeding and retinal detachment.Therefore, inhibition of pathological RNV is […]

Inhibitory effects of jiajianzhujing decoction containing serum on proliferation of rat choroidal vascular endothelial cells

Authors:Liu Yanjiang,  Kang Zefeng,  Xing Kai,  Liu Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.12.003 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1065-1071. Abstract                              [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) of macular zone is one of blinding eye diseases.Conventional treatment methods include photodynamic therapy and intravitreal injection of anti-vascular endothelial growth […]

Development of cooperative robot-assistant surgery system for vitreoretinal microsurgery and its feasibility test in an animal model

Authors: Chen Yiqi,  Zhang Chaote,  Hong Mingsheng,  Su Lingya,  Tao Jiwei,  Yang Yang,  Xiao Jingjing,  Shen Lijun DOI: 10.3760/cma.j.issn.2095-0160.2017.01.008 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 38-41. Abstract                               [Download PDF] [Read Full Text] Background Robotic systems are increasingly utilized in numerous disciplines including ophthalmology.Several reports showed potential benefits of robotic-assisted surgery, […]

Protection of sericin to retinal microvessels and its mechanism in diabetic rats

Authors: Yu Hongfei,  Dong Zhijun,  Zhang Tiemin,  Yang Fan DOI: 10.3760/cma.j.issn.2095-0160.2017.01.007 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 32-37. Abstract                              [Download PDF] [Read Full Text] Background Diabetic retinopathy (DR) is a chronic inflammatory disease, with pathological changes of retinal microvessels.Studies demonstrated that sericin has anti-inflammation and anti-oxidation […]

Relationship of human microvascular endothelial cell activation and adenosine level under the hypoxia

Authors: Ai Liqianyu,  Huang Chanjuan,  Chen Chen,  Lin Sen,  Ye Jian DOI: 10.3760/cma.j.issn.2095-0160.2017.01.006 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 26-31. Abstract                              [Download PDF] [Read Full Text] Background Retinal hypoxia is one of primary causes of retinal neovascularization, and its mechanism is research hot topic.Studies showed that hypoxia […]

Modified primary culture and identification of human retinal Müller cells

Authors: Lin Shaofen,  Mao Yuxiang,  Xie Manyun,  Tang Shibo DOI: 10.3760/cma.j.issn.2095-0160.2017.01.005 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 22-25. Abstract                            [Download PDF] [Read Full Text] Background Retinal Müller cells are important gliocytes and the source of retinal stem cells.Researching the biological behavior of Müller cells is of important […]

Dynamic changes of FasL protein expression in retinal tissue with aging in retinal degeneration mice

Authors: Tian J,  Li Genlin  DOI: 10.3760/cma.j.issn.2095-0160.2017.01.004 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 17-21. Abstract                              [Download PDF] [Read Full Text] Background Retinal transplantation is a new approach to the treatment of retinal degeneration diseases, and how to avoid or reduce the immune rejection after […]