Authors: Li Jingwen, Li Guowen, Lu Jun, Li Chunxia DOI: 10.3760/cma.j.issn.2095-0160.2017.07.008 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 611-616. Abstract [Download PDF] [Read Full Text] Background The pathogenesis of diabetic retinopathy (DR) involves a variety of biological pathways.Recently, inflammation factor has been thought to paly an important […]
Category: Experimental Science
Protective effects of tissue factor targeting peptide on human retinal pigment epithelial cell damage induced by blue light
Authors: Li Dandan, Zou Xiulan, Chen Jingxia, Xu Zhe, Yu Yongzhen, Zhou Wenjie, Wang Guanfeng, Rao Benqiang, Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2017.07.006 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 603-609. Abstract [Download PDF] [Read Full Text] Background Light-induced retinal damage results in the damage of retinl pigment epithelial (RPE) cells and therefore affects […]
Regulation of high glucose to the expression of Toll-like receptor 4 in retinal ganglion cells and its significance
Authors: Hu Lili, Ai Ming, Yang Hongxia, Jiang Shuanghong DOI: 10.3760/cma.j.issn.2095-0160.2017.07.005 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 597-602. Abstract [Download PDF] [Read Full Text] Background Studies show that retinal neurodegeneration may precede retinal microvascular changes in diabetes mellitus.The apoptosis of retinal ganglion cells (RGCs) is an […]
Photobiomodulation of light emitting diode irradiation on apoptosis of retinal neuronal cells induced by high-glucose
Authors: Zhang Limin, Zhang Fengjiu, Lin Anling, Peng Xiangdong, Yang Jianling, Yu Lingyan, Wang Haiming, Gao Shikai DOI: 10.3760/cma.j.issn.2095-0160.2017.07.004 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 591-596. Abstract [Download PDF] [Read Full Text] Background To study the pathogenesis and management of diabetic retinopathy (DR) has an important clinical significance.With the development […]
Inhibitory effects of apolipoprotein A-Ⅰ on biological behavior and VEGF expression of human retinal epithelial cells in high glucose environment
Authors: Tan Chengye, Shao Jun, Zhuang Miao, Yao Yong DOI: 10.3760/cma.j.issn.2095-0160.2017.07.003 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 586-590. Abstract [Download PDF] [Read Full Text] Background As a main cellular component of retinal microvascular, retinal vascular endothelial cells (RVECs) play critical roles in the occurrence and development […]
Protection effects of metformin on biological behaviour of human vascular endothelial cells under inflammatory conditions
Authors: Han Jing, Yan Xiaolong, Xiaoxi Qiao DOI: 10.3760/cma.j.issn.2095-0160.2017.07.002 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 581-585. Abstract [Download PDF] [Read Full Text] Background Studies showed that inflammatory process participates in the pathogenesis and development of diabetic retinopathy targeting retinal vascular endothelial […]
Inhibitory effects of microRNA-375 on biological behaviour of human retinal capillary endothelial cells induced by hypoxia
Authors: Zhu Jiang, Ren Mei, Xu Zhiguo DOI: 10.3760/cma.j.issn.2095-0160.2017.08.005 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 695-702. Abstract [Download PDF] [Read Full Text] Background Studies showed that microRNA (miR)-375 suppresses the growth, apoptosis, migration and adhesion of tumor cells, and it plays a regulation to the […]
Aggravation effects of JAK-STAT signaling pathway in retinal ischemia reperfusion injury
Authors: Yang Le, Shi Rui, Shen Jiaquan, Xue Yushun DOI: 10.3760/cma.j.issn.2095-0160.2017.08.004 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 690-694. Abstract [Download PDF] [Read Full Text] Background Retinal ischemia reperfusion injury (RIRI) is a common pathological process of many retinal vascular diseases with comprehensive pathogenesis mechanism.Researches showed that […]
Construction of combined lentiviral vectors for rat Slit2 gene RNA interfering and its down-regulation effects on Slit2 gene in rat retinal pigment epithelial cells
Authors: Jiang Shaoqiu, Zhou Xiyuan DOI: 10.3760/cma.j.issn.2095-0160.2017.08.003 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 683-689. Abstract [Download PDF] [Read Full Text] Background Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years old, of which 90% cases are caused by […]
Inhibition of adenovirus-mediated recombinant Tum5 gene overexpression on human umbilical vein endothelial cells in physiological status
Authors: Jia Yurong, Yang Wei, Zhang Hong, Zhang Yan, Sun Jing DOI: 10.3760/cma.j.issn.2095-0160.2017.08.002 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 677-682. Abstract [Download PDF] [Read Full Text] Background Tumstatin is the most active endogenous angiogenesis inhibitor, which has a marked inhibitory effect on pathological neovascularization, and Tum5 is […]