Category: Experimental Science

A comparative study on the inhibitory effects of commonly used clinical drugs on in vitro fibroblasts from recurrent pterygium

Authors: Sun Yajie,  Lin Tingting,  He Yanjin,  Zhu Limin,  Gao Yang,  Zhou Bo DOI: 10.3760/cma.j.issn.2095-0160.2017.06.006 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 512-519. Abstract                              [Download PDF] [Read Full Text] Background Pterygium is one of the common ocular surface disorders, and the main drugs for pterygium include dexamethasone (DXM), interferon […]

Influence of high intensity focused ultrasound irradiating cornea on retinas of living rabbits

Authors: Li Meixuan,  Du Zhiyu,  Wang Menglei,  Yan Pisong,  Zhang Yu,  Li Chongyan  DOI: 10.3760/cma.j.issn.2095-0160.2017.06.005 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 506-511. Abstract                               [Download PDF] [Read Full Text] Background High intensity focused ultrasound (HIFU) is a novel noninvasive technique and it has been used to clinical treatment of […]

Combinatorial protective effects of α-melanocyte-stimulating hormone and carboxymethylcellulose on ocular surface in dry eye rat models

Authors: Dou Zexia,  Ru Yusha,  Liu Huijuan,  Zeng Xiaoyu,  Meng Zhu,  Gu Zhongxiu,  Zhang Yan,  Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2017.06.004 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 498-505. Abstract                              [Download PDF] [Read Full Text] Background Reasearches showed that α-melanocyte-stimulating hormone (α-MSH) inhibits inflammation and ameliorates the ocular surface abnormalities in a scopolamine-induced […]

Dynamic expression changes of Smad3 and type Ⅰ collagen in sclera of progressive myopia in guinea pigs

Authors: Jiang Bo,  Wu Zhangyou,  Zhu Zicheng,  Hu Wei,  Zhan Xin DOI: 10.3760/cma.j.issn.2095-0160.2017.06.003 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 491-497. Abstract                              [Download PDF] [Read Full Text] Background Sclera remodeling process in axial elongation is one of the main pathological mechanisms of axial myopia progression.Studies confirmed that transforming […]

Dynamic expression of conventional protein kinase C-γ with development of visual cortex and effect of monocular deprivation on it in mice

Authors: Xi Ping,  Wang Jing,  Han Song,  Li Junfa,  Fu Tao DOI: 10.3760/cma.j.issn.2095-0160.2017.06.002 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 486-490. Abstract                               [Download PDF] [Read Full Text] Background Plasticity of visual system is one of the mechanisms of deprivation amblyopia.Our previous study showed that synapsin plays a role […]

Protection of polysaccharides of dendrobium candidum on blood-retinal barrier in diabatic rats and its mechanism

Authors: Li Jingwen,  Li Guowen,  Lu Jun,  Li Chunxia DOI: 10.3760/cma.j.issn.2095-0160.2017.07.008 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 611-616. Abstract                              [Download PDF] [Read Full Text] Background The pathogenesis of diabetic retinopathy (DR) involves a variety of biological pathways.Recently, inflammation factor has been thought to paly an important […]

Protective effects of tissue factor targeting peptide on human retinal pigment epithelial cell damage induced by blue light

Authors: Li Dandan,  Zou Xiulan,  Chen Jingxia,  Xu Zhe,  Yu Yongzhen,  Zhou Wenjie,  Wang Guanfeng,  Rao Benqiang,  Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2017.07.006 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 603-609. Abstract                               [Download PDF] [Read Full Text] Background Light-induced retinal damage results in the damage of retinl pigment epithelial (RPE) cells and therefore affects […]

Regulation of high glucose to the expression of Toll-like receptor 4 in retinal ganglion cells and its significance

Authors: Hu Lili,  Ai Ming,  Yang Hongxia,  Jiang Shuanghong DOI: 10.3760/cma.j.issn.2095-0160.2017.07.005 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 597-602. Abstract                              [Download PDF] [Read Full Text] Background Studies show that retinal neurodegeneration may precede retinal microvascular changes in diabetes mellitus.The apoptosis of retinal ganglion cells (RGCs) is an […]

Photobiomodulation of light emitting diode irradiation on apoptosis of retinal neuronal cells induced by high-glucose

Authors: Zhang Limin,  Zhang Fengjiu,  Lin Anling,  Peng Xiangdong,  Yang Jianling,  Yu Lingyan,  Wang Haiming,  Gao Shikai DOI: 10.3760/cma.j.issn.2095-0160.2017.07.004 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 591-596. Abstract                              [Download PDF] [Read Full Text] Background To study the pathogenesis and management of diabetic retinopathy (DR) has an important clinical significance.With the development […]

Inhibitory effects of apolipoprotein A-Ⅰ on biological behavior and VEGF expression of human retinal epithelial cells in high glucose environment

Authors: Tan Chengye,  Shao Jun,  Zhuang Miao,  Yao Yong  DOI: 10.3760/cma.j.issn.2095-0160.2017.07.003 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 586-590. Abstract                              [Download PDF] [Read Full Text] Background As a main cellular component of retinal microvascular, retinal vascular endothelial cells (RVECs) play critical roles in the occurrence and development […]