Category: 2017, No. 05

Recent advances of micro RNA in neovascularization formation of diabetic retinopathy

Authors: Huang Jun,  Mao Xinbang DOI: 10.3760/cma.j.issn.2095-0160.2017.05.020 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 478-480. Abstract MicroRNA (miRNA) is a kind of endogenous and highly conservative RNA, with length of about 20 to 24 nucleotides and tissue specificity.MiRNA regulates the expression of target genes by pairing with complementary mRNA in the transcription level mRNA or […]

Advancement of endostatin on inhibiting neoangiogenesis of diabetic retinopathy

Authors: Zhang Ming,  Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2017.05.018 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 474-477. Abstract Diabetic retinopathy (DR) is a common disease of ophthalmology, often causes irreversible decline of patients’ vision, which has two features including macular oedema, diabetic retinal neovascularization.Diabetic retinal neovascularization is one of the most important reasons leading to blindness.Endostatin (ES) […]

Application of optical coherence tomography angiography for ophthalmology

Authors: Yang Mo,  Wei Shihui,  Xu Quangang DOI: 10.3760/cma.j.issn.2095-0160.2017.05.017 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 469-473. Abstract Optical coherence tomography angiography (OCTA) is a new emerging technology that is widely used in diagnosis of ocular diseases recently.It has the capability to generate high resolution 3D angiograms of retina and choroid, dissect and visualize the flow […]

Research progress of intervention treatment on the retinal ischemia-reperfusion injury

Authors: Zhang Xue,  Sun Dawei DOI: 10.3760/cma.j.issn.2095-0160.2017.05.016 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 463-467. Abstract Retinal ischemia-reperfusion injury (RIRI) is a common pathological and physiological clinical oculopathy, which can occur in retinal artery and vein occlusion, diabetic retinopathy and acute angle-closure glaucoma.The resulting ischemia can cause cell metabolic dysfunction, serious retinal damage and descending […]

Morphological evalution of obstructive meibomian gland dysfunction by noninvasive Keratograph

Authors: Yang Liu,  Meng Zhu,  Zhao Jinrong,  Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2017.05.015 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 458-462. Abstract Background Obstructive meibomian gland dysfunction (OMGD) is due to the meibomian gland duct obstruction and/or meibum abnormal secretion.Meibomian gland morphological change is important to clinical observation. Objective This study aimed to image the meibomian gland structures and […]

The accuracy and clinical significance of ultrasound biomicroscopy observing zonule situation

Authors: Wu Bin,  Wu Di,  Zhou Zhen,  He Guanghui,  Wang Jian,  Xu Zhigang,  Chen Song,  Li Yan DOI: 10.3760/cma.j.issn.2095-0160.2017.05.014 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 453-457. DOI: 10.3760/cma.j.issn.2095-0160.2017.05.014 Abstract Background The situation of zonule is very important for determining the cataract surgery.Ultrasound biomicroscopy (UBM) is an important method to observe the situation of zonule before cataract surgery. Objective This study […]

Application of subtenon injection of triamcinolone acetonide combined with vitrectomy in the treatment of retinal detachment with choroidal detachment

Authors: Mao Jianbo,  Wu Sulan,  Chen Yiqi,  Jiang Lu,  Chu Mengqi,  Dong Yugui,  Tao Jiwei,  Lin Li,  Shen Lijun DOI: 10.3760/cma.j.issn.2095-0160.2017.05.013 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 448-452. Abstract Background The introvitreal injection of triamcinolone acetonide (TA) before vitrectomy for retinal with choroidal detachment (RD/CD) can alleviate inflammatory response, but it easily lead to complications under the low intraocular pressure.The study […]

Management and pathology of the optical area fibrotic membrane underlying preserved anterior capsule after lensectomy

Authors: Yang Ming,  Zhang Yuanxia,  Zhang Li,  Chen Shu,  Wang Zhijun DOI: 10.3760/cma.j.issn.2095-0160.2017.05.012 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 443-447. Abstract Background Lensectomy with anterior capsule preserving is still advisable under specific conditions during vitrectomy.Although lens epithelial cells were polished off during surgery, opacification in varying degrees could be observed.Understanding the composition of proliferative anterior capsule membrane […]

Anastalsis of triamcinolone acetonide during vitrectomy in proliferative diabetic retinopathy

Authors: Zhou Yanjie,  You Caiyun,  Wang Tian,  Zhang Mingxue,  Song Yinting,  Liao Mengyu,  Han Han,  Zhang Zhuhong,  Li Jianan,  Yan Hua DOI: 10.3760/cma.j.issn.2095-0160.2017.05.011 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 439-442. Abstract Background Clinical work found that triamcinolone acetonide (TA)bleeding during vitrectomy in proliferative diabetic retinopathy (PDR), but its mechanism is not clear. Objective This study was to explore the anastalsis of TA […]

Excitatory toxicity of glutamate on meningothelial cells of optic nerve sheaths and its oxidative stress mechanism

Authors: Xin Xiaorong,  Gong Tianxiang,  Hong Ying,  Dang Hong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.009 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 432-437. Abstract Background Meningothelial cells (MECs) occupy the predominant cell component of barrier between optic nerve and the cerebral spinal fluid, and any change of cerebral fluid components probably affects the MECs function and further impairs the optic nerve. […]