Authors: Cheng Rong, Zhang Lu, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2018.06.005 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 424-428. Abstract [Download PDF] [Read Full Text] Objective To investigate the role of autophagy in the development of diabetic cataract by detecting the expression of autophagy-related […]
Category: Experimental Science
Protection effect of endomucin on retinal neurons and its mechanism in streptozotocin-induced diabetic rat
Authors: Niu Tian, Xie Liping, Xing Xindan, Jiang Yan, Jin Huiyi, Wang Haiyan, Liu Kun DOI: 10.3760/cma.j.issn.2095-0160.2018.06.004 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 417-423. Abstract [Download PDF] [Read Full Text] Objective To investigate the change of endomucin(EMCN) expression in diabetic retinopathy(DR) and its protective role in neurons apoptosis. Methods […]
The alterations of PGC-1α expression and epigenetic modifications in the retina of streptozotocin-induced diabetic rats
Authors: Geng Shuang, Chen Youxin, Yao Xiang, Xu Haiyan, Zhang Gumuyang, Xia Song, Liu Ziyang DOI: 10.3760/cma.j.issn.2095-0160.2018.06.003 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 410-416. Abstract [Download PDF] [Read Full Text] Objective To investigate the role of epigenetic regulations of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) in the development […]
Effects of long noncoding RNA-MIAT on lens epithelial to mesenchymal transition induced by transforming growth factor-β2
Authors: Yue Xiujuan, Su Sheng, Wang Liyuan, Lyu Jia, Wang Lin, Liu Ping DOI: 10.3760/cma.j.issn.2095-0160.2018.07.005 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 508-513. Abstract [Download PDF] [Read Full Text] Objective To investigate the roles of long noncoding RNA-myocardial infarction-associated transcript (MIAT) on lens epithelial cells (LECs) fibrosis induced by […]
Expression dynamics of lens development-associated transcription factors in human embryonic stem cell-induced lentoid body
Authors: Han Chenlu, Wang Chunxiao, Li Jinyan, Luo Lixia DOI: 10.3760/cma.j.issn.2095-0160.2018.07.004 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 500-507. Abstract [Download PDF] [Read Full Text] Objective To observe the expression dynamics of lens-related transcription factors in human embryonic stem cell (hESC) differentiated into lentoid body(LB). Methods A […]
Changes of mitochondrial dynamics related genes expression in a glaucoma rat model
Authors: Hu Xinxin, Dai Yi, Sun Xinghuai DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]
Effect of Eylea on recombinant AAV2-VEGF-induced choroidal neovascularization
Authors: Jiang Laisheng, Liao Qin, Cai Keyang, Sun Huiye, Sun Yunxia DOI: 10.3760/cma.j.issn.2095-0160.2018.08.008 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 608-612. Abstract [Download PDF] [Read Full Text] Objective To evaluate the effect of Eylea (aflibercept) on recombinant adeno-associated virus 2(AAV2)-vascular endothelial growth factor (VEGF)-induced choroidal neovascularization (CNV). Methods […]
The suppression mechanisms of quercetin in retinal and choroidal neovascularization through integrin signal pathway
Authors: Yue Yankun, Wang Haiwei, Deng Yu, Tian Mo, Wang Yinlin, Zhang Enkui DOI: 10.3760/cma.j.issn.2095-0160.2018.08.007 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 602-607. Abstract [Download PDF] [Read Full Text] Objective To investigate the mechanisms of quercetin in retinal angiogenesis via in vitro and in vivo studies. Methods Human umbilical […]
The dynamic expression of CD146 in corneal neovascularization and its significance
Authors: Wang He, Li Mingxin DOI: 10.3760/cma.j.issn.2095-0160.2018.08.005 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 596-600. Abstract [Download PDF] [Read Full Text] Objective To investigate the expression and localization of CD146 in corneal neovascularization. Methods Fifty SPF male SD rats with the […]
Changes of Kir4.1 and TASK-1 expression in rat Müller cell induced by SCH442416 at an elevated hydrostatic pressure in vitro
Authors: Yang Zijian, Cheng Yu, Yao Huiping, Shen Ting, Chen Yanwei, Zhong Yisheng DOI: 10.3760/cma.j.issn.2095-0160.2018.08.003 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 590-594. Abstract [Download PDF] [Read Full Text] Objective To evaluate the effect of adenosine receptor antagonist SCH442416 on the expression of Kir2.1, Kir4.1 and TASK-1 in rat […]