Category: Experimental Science

Comparison of pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E1 and RC28-E2 in retinal angiogenesis and neovascularization and its mechanism

Authors: Gu Zhongxiu,  Jiang Jing,  Huang Min,  Wu Mianmian,  Guo Fang,  Li Shenjun,  Fang Jianmin,  Zhao Shaozhen,  Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2018.08.002 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 581-589. Abstract                               [Download PDF] [Read Full Text] Objective To compare the pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E1 and RC28-E2 […]

Growth characteristics of Aspergillus isolated from clinical infective cornea

Authors: Li Yingyu,  Zhang Pei,  Huang Chen,  Liu Ziyuan,  Liu Cong,  Zhang Wei,  Dong Xuhe,  Wang Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.09.006 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 683-687. Abstract                               [Download PDF] [Read Full Text] Objective To analyze the growth characteristics of the clinical isolates of Aspergillus compared to standard strains in vitro. […]

Expression of p53 and its effect on microRNA-29b expression in the process of normal human conjunctival fibroblasts transforming to myofibroblast

Authors: Yan Weiling,  Liao Rongfeng,  Li Ning DOI: 10.3760/cma.j.issn.2095-0160.2018.09.004 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 676-681. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the relationship between p53 and miR-29b in myofibroblasts (MFs) induced from human Tenon fibroblasts (HTFs). Methods Human Tenon tissues were […]

Establishment of apoptosis model in mouse cone cell line 661W cells and the primary research on protective effects of autophagy

Authors:  Gao Wenna,  Xie Jia,  Du Jiantong,  Zhu Ruilin,  Yang Liu DOI: 10.3760/cma.j.issn.2095-0160.2018.09.003 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 666-675. Abstract                              [Download PDF] [Read Full Text] Objective To establish the apoptosis model in mouse cone cell line 661W cells and to investigate the viability of 661W cells […]

Pulsed and continuous accelerated scleral cross-linking using riboflavin and ultraviolet A irradiation for the prevention of myopia progression in a guinea pig model

Authors: Xu Haiming,  Liu Hui,  Yu Jie,  He Jinjing DOI: 10.3760/cma.j.issn.2095-0160.2018.10.006 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 767-772. Abstract                               [Download PDF] [Read Full Text] Objective To evaluated the effect of oral administration of riboflavin combined with pulsed and continuous light accelerated scleral cross-linking on the histological […]

Stimulating effects of conjunctival sac implants after eye enucleation on orbital bone tissue in rabbits

Authors:  Liu Xiaoying,  Hu Zhulin,  Kang Jianshu,  Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2018.10.005 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 761-766. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the stimulating effects of conjunctival sac implants following eye enucleation on orbital bone tissue in rabbits model. Methods Eighty […]

Expression of metastasis associated genes nm23, p53 and S100A4 in conjunctival melanoma and their relationship with invasion and metastasis

Authors: Xie Kunpeng,  Liu Ping,  Wang Xin DOI: 10.3760/cma.j.issn.2095-0160.2018.10.004 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 756-760. Abstract                               [Download PDF] [Read Full Text] Objective To study the significance of metastasis associated genes nm23, p53 and S100A4 in the development of conjunctival melanoma metastasis. Methods Conjunctival melanoma […]

Effects of lentivirus-mediated knockdown of astrocyte elevated gene-1 on the biological behavior of uveal melanoma

Authors: Mao Ying,  Bai Haixia,  Chang Ying,  Li Bin DOI: 10.3760/cma.j.issn.2095-0160.2018.10.003 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 748-755. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effects of lentivirus-mediated knockdown of astrocyte elevated gene-1 (AEG-1) on the biological behavior of uveal melanoma(UM). Methods MUM-2B […]

c-Fos expression in visual cortex of infant rhesus monkeys with myopia induced by hyperopic defocus

Authors: Wu Junshu,  Sha Xiangyin,  Zheng Hua,  Liu Yinghui,  Ge Jian DOI: 10.3760/cma.j.issn.2095-0160.2018.11.006 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 847-851. Abstract                               [Download PDF] [Read Full Text] Objective To observe c-Fos expression in visual cortex of infant rhesus monkeys with myopia induced by hyperopic defocus and preliminarily investigate […]

Changes of the immune-microenvironment in retinal degeneration process of RCS rat

Authors:  Tang Huanyu,  Lu Ziyang,  He Juncai,  Gao Yuan,  Yin Zhengqin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.005 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 839-846. Abstract                               [Download PDF] [Read Full Text] Objective To explore the immune-microenvironment of the retinas at different stages of retinal degeneration in Royal College of Surgeon (RCS) rats. […]