Authors: Tu Yanqiong, Luo Yulin, Liu Zhenghai, Wu Xiaoying DOI: 10.3760/cma.j.issn.2095-0160.2018.05.003 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 330-336. Abstract [Download PDF] [Read Full Text] Objective This study was to investigate the effect of caloric restriction on the plasticity of visual cortex in adult monocular deprivation (MD) […]
Category: Experimental Science
Protective effect of leukemia inhibitory factor on light induced retinal photoreceptors damage and its mechanisms
Authors: Dong Shuqian, Liu Shuangzhen, Li Qiuming DOI: 10.3760/cma.j.issn.2095-0160.2018.06.007 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 435-440. Abstract [Download PDF] [Read Full Text] Objective To investigate the role of leukemia inhibitory factor (LIF) on retinal photoreceptor cells and the underlying mechanism after light damage. Methods Fifty […]
Comparison of different doses streptozotocin-induced mouse models for the research of type 1 diabetic keratopathy
Authors: Zhang Zhenzhen, Hu Xiaoli, Hua Yingbin, Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2018.06.006 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 429-434. Abstract [Download PDF] [Read Full Text] Objective To compare the rates and pathological features of diabetic keratopathy in mice induced by single high dose […]
The expression change of autophagy-related factors in lens epithelial cells of diabetic mice
Authors: Cheng Rong, Zhang Lu, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2018.06.005 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 424-428. Abstract [Download PDF] [Read Full Text] Objective To investigate the role of autophagy in the development of diabetic cataract by detecting the expression of autophagy-related […]
Protection effect of endomucin on retinal neurons and its mechanism in streptozotocin-induced diabetic rat
Authors: Niu Tian, Xie Liping, Xing Xindan, Jiang Yan, Jin Huiyi, Wang Haiyan, Liu Kun DOI: 10.3760/cma.j.issn.2095-0160.2018.06.004 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 417-423. Abstract [Download PDF] [Read Full Text] Objective To investigate the change of endomucin(EMCN) expression in diabetic retinopathy(DR) and its protective role in neurons apoptosis. Methods […]
The alterations of PGC-1α expression and epigenetic modifications in the retina of streptozotocin-induced diabetic rats
Authors: Geng Shuang, Chen Youxin, Yao Xiang, Xu Haiyan, Zhang Gumuyang, Xia Song, Liu Ziyang DOI: 10.3760/cma.j.issn.2095-0160.2018.06.003 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 410-416. Abstract [Download PDF] [Read Full Text] Objective To investigate the role of epigenetic regulations of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) in the development […]
Effects of long noncoding RNA-MIAT on lens epithelial to mesenchymal transition induced by transforming growth factor-β2
Authors: Yue Xiujuan, Su Sheng, Wang Liyuan, Lyu Jia, Wang Lin, Liu Ping DOI: 10.3760/cma.j.issn.2095-0160.2018.07.005 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 508-513. Abstract [Download PDF] [Read Full Text] Objective To investigate the roles of long noncoding RNA-myocardial infarction-associated transcript (MIAT) on lens epithelial cells (LECs) fibrosis induced by […]
Expression dynamics of lens development-associated transcription factors in human embryonic stem cell-induced lentoid body
Authors: Han Chenlu, Wang Chunxiao, Li Jinyan, Luo Lixia DOI: 10.3760/cma.j.issn.2095-0160.2018.07.004 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 500-507. Abstract [Download PDF] [Read Full Text] Objective To observe the expression dynamics of lens-related transcription factors in human embryonic stem cell (hESC) differentiated into lentoid body(LB). Methods A […]
Changes of mitochondrial dynamics related genes expression in a glaucoma rat model
Authors: Hu Xinxin, Dai Yi, Sun Xinghuai DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]
Effect of Eylea on recombinant AAV2-VEGF-induced choroidal neovascularization
Authors: Jiang Laisheng, Liao Qin, Cai Keyang, Sun Huiye, Sun Yunxia DOI: 10.3760/cma.j.issn.2095-0160.2018.08.008 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 608-612. Abstract [Download PDF] [Read Full Text] Objective To evaluate the effect of Eylea (aflibercept) on recombinant adeno-associated virus 2(AAV2)-vascular endothelial growth factor (VEGF)-induced choroidal neovascularization (CNV). Methods […]