Category: Experimental Science

Antifungal efficacy of corneal collagen cross-linking on treating experimentally induced fungal keratitis of mice

Authors: Zhu Ziqian,  Qiu Shuanghao,  Yue Juan,  Liu Susu,  Gu Lizhe,  Zhang Hongmin,  Li Zhijie,  Wang Liya DOI: 10.3760/cma.j.issn.2095-0160.2018.05.005 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 344-350. Abstract                               [Download PDF] [Read Full Text] Objective This study was to assess the efficacy of corneal collagen cross-linking treatment on fungal keratitis. Methods Eighty […]

Morphology of intrinsically photosensitive retinal ganglion cells: distinct photoreceptors from rod/cone photoreceptors

Authors: Hu Caiping,  Xu Wenjun,  Jin Xuemin DOI: 10.3760/cma.j.issn.2095-0160.2018.05.004 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 337-343. Abstract                              [Download PDF] [Read Full Text] Objective This study was to observe the morphology of live intrinsically photosensitive retinal ganglion cells (ipRGCs) at cellular level, […]

Reactivation of visual cortical plasticity by caloric restriction mediated by AMPK-SIRT1 pathway from monocular deprivation in adult mice

Authors: Tu Yanqiong,  Luo Yulin,  Liu Zhenghai,  Wu Xiaoying DOI: 10.3760/cma.j.issn.2095-0160.2018.05.003 Published 2018-05-10 Cite as Chin J Exp Ophthalmol, 2018,36(5): 330-336. Abstract                               [Download PDF] [Read Full Text] Objective This study was to investigate the effect of caloric restriction on the plasticity of visual cortex in adult monocular deprivation (MD) […]

Protective effect of leukemia inhibitory factor on light induced retinal photoreceptors damage and its mechanisms

Authors: Dong Shuqian,  Liu Shuangzhen,  Li Qiuming DOI: 10.3760/cma.j.issn.2095-0160.2018.06.007 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 435-440. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the role of leukemia inhibitory factor (LIF) on retinal photoreceptor cells and the underlying mechanism after light damage. Methods Fifty […]

Comparison of different doses streptozotocin-induced mouse models for the research of type 1 diabetic keratopathy

Authors:  Zhang Zhenzhen,  Hu Xiaoli,  Hua Yingbin,  Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2018.06.006 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 429-434. Abstract                              [Download PDF] [Read Full Text] Objective To compare the rates and pathological features of diabetic keratopathy in mice induced by single high dose […]

The expression change of autophagy-related factors in lens epithelial cells of diabetic mice

Authors: Cheng Rong,  Zhang Lu,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2018.06.005 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 424-428. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the role of autophagy in the development of diabetic cataract by detecting the expression of autophagy-related […]

Protection effect of endomucin on retinal neurons and its mechanism in streptozotocin-induced diabetic rat

Authors: Niu Tian,  Xie Liping,  Xing Xindan,  Jiang Yan,  Jin Huiyi,  Wang Haiyan,  Liu Kun DOI: 10.3760/cma.j.issn.2095-0160.2018.06.004 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 417-423. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the change of endomucin(EMCN) expression in diabetic retinopathy(DR) and its protective role in neurons apoptosis. Methods […]

The alterations of PGC-1α expression and epigenetic modifications in the retina of streptozotocin-induced diabetic rats

Authors: Geng Shuang,  Chen Youxin,  Yao Xiang,  Xu Haiyan,  Zhang Gumuyang,  Xia Song,  Liu Ziyang DOI: 10.3760/cma.j.issn.2095-0160.2018.06.003 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 410-416. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the role of epigenetic regulations of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) in the development […]

Effects of long noncoding RNA-MIAT on lens epithelial to mesenchymal transition induced by transforming growth factor-β2

Authors: Yue Xiujuan,  Su Sheng,  Wang Liyuan,  Lyu Jia,  Wang Lin,  Liu Ping DOI: 10.3760/cma.j.issn.2095-0160.2018.07.005 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 508-513. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the roles of long noncoding RNA-myocardial infarction-associated transcript (MIAT) on lens epithelial cells (LECs) fibrosis induced by […]

Expression dynamics of lens development-associated transcription factors in human embryonic stem cell-induced lentoid body

Authors: Han Chenlu,  Wang Chunxiao,  Li Jinyan,  Luo Lixia DOI: 10.3760/cma.j.issn.2095-0160.2018.07.004 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 500-507. Abstract                              [Download PDF] [Read Full Text] Objective To observe the expression dynamics of lens-related transcription factors in human embryonic stem cell (hESC) differentiated into lentoid body(LB). Methods A […]