Category: Review

Research progress on the microbiota of ocular surface

2018, No. 09, Review

Authors: An Na,  Liu Xianning DOI: 10.3760/cma.j.issn.2095-0160.2018.09.012 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 714-718. Abstract                               [Download PDF] [Read Full Text] The microbiota of the ocular surface consists of diverse microbial communities and colonizes on the ocular mucous membrane including tear film.The symbiotic relationship maintains […]

Mitochondrial damage and related ocular disorders

2018, No. 10, Review

Authors: Chen Qiang,  Liang Lina DOI: 10.3760/cma.j.issn.2095-0160.2018.10.017 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 812-816. Abstract                               [Download PDF] [Read Full Text] Mitochondria are recognized to function as the powerhouse of the cell.The etiology of many common ocular disorders is increasingly recognized to involve either an […]

Progress in research of nicotinamide adenine dinucleotide imbalance mediated retinal neurodegeneration

2018, No. 10, Review

Authors: Liu Yang,  Luo Xueting DOI: 10.3760/cma.j.issn.2095-0160.2018.010.016 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 808-811. Abstract                               [Download PDF] [Read Full Text] Nicotinamide adenine dinucleotide (NAD+ ) is a critical mediator in biochemical reactions.It serves both as a coenzyme in reduction-oxidation reactions, and as a cosubstrate […]

Tear components in thyroid associated ophthalmopathy

2018, No. 10, Review

Authors: Fan Xiaotian,  Wei Ruili DOI: 10.3760/cma.j.issn.2095-0160.2018.10.014 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 800-803. Abstract                              [Download PDF] [Read Full Text] Thyroid associated ophthalmopathy (TAO) is the most common autoimmune inflammatory orbital disease in adults.Because of its high incidence and the […]

Progress of GNAQ/GNA11 mutation in uveal melanoma

2018, No. 10, Review

Authors: Zheng Lei,  Zhang Guoming DOI: 10.3760/cma.j.issn.2095-0160.2018.10.012 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 791-795. Abstract                               [Download PDF] [Read Full Text] Uveal melanoma (UM) is the most common primary intraocular tumor in adults, which not only affects patients’ visual function, but easily leads to death.Despite […]

Applications of CRISPR/Cas9 genome editing technology in gene therapy for hereditary eye diseases

2018, No. 11, Review

Authors:  Wu Shijing,  Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2018.11.016 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 892-896. Abstract                               [Download PDF] [Read Full Text] Clustered regulatory interspaced short palindromic repeat (CRISPR)/CRISPR associated nuclease (Cas) system is an adaptive immune system that confers resistance to exogenous virus or plasmid […]

Research progress of ocular surface reconstruction with ex vivo cultured tissue engineered cell sheet

2018, No. 11, Review

Authors:  Wang Fuyan,  Zhou Qingjun,  Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.015 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 887-891. Abstract                              [Download PDF] [Read Full Text] Limbal stem cells (LSCs), the source of corneal epithelial cells, play an important role in the ocular surface.In recent […]

Research progress of stem cells in corneal wound healing

2018, No. 11, Review

Authors: Chen Hongli,  Yan Chenxi,  Fu Yao DOI: 10.3760/cma.j.issn.2095-0160.2018.11.014 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 883-886. Abstract                              [Download PDF] [Read Full Text] As the outermost part, cornea plays a critical role in protecting the eyeball and functions as main component of the dioptric media.Trauma, inflammation, […]