Progress in pathogenesis and treatment of the elevated intraocular pressure resulted from thyroid associated ophthalmopathy

Authors: Guo Zhenfeng,  Zhao Liang,  Sun Fengyuan
DOI: 10.3760/cma.j.cn115989-20191022-00459
Published 2021-07-10
Cite asChin J Exp Ophthalmol, 2021, 39(7): 661-664.

Abstract

In adult orbital diseases, thyroid associated ophthalmopathy (TAO) is of very high incidence rate, and it can seriously affect patients’ appearance, eyesight and binocular visual function and so on, and significantly reduce the patients’ quality of life.In addition to the common manifestations such as eyelid retraction, exophthalmos and strabismus, some TAO patients may suffer from obviously increased ocular pressure and even visual field damage, which are often ignored or missed in diagnosis and should be paid more attention to.The pathogenesis of elevated intraocular pressure in TAO is mainly related to the elevated episcleral venous pressure and the extraocular muscles.Because the elevated intraocular pressure resulted from TAO is secondary and its pathogenesis is complex, personalized treatment different from primary glaucoma therapy is needed.In this article, the epidemiology, pathogenesis and therapy of elevated intraocular pressure in TAO including medication, surgery, and radiotherapy were reviewed to provide reference for the clinical diagnosis and treatment for TAO.

Key words:

Thyroid associated ophthalmopathy; Elevated intraocular pressure; Pathogenesis; Treatment

Contributor Information

Guo Zhenfeng
Tianjin Beichen Hospital, Tianjin 300400, China
Zhao Liang

Tianjin Medical University Eye Hospital, School of Optometry and Ophthalmology, Tianjin Medical University Eye Institute, Tianjin 300384, China

Sun Fengyuan

Tianjin Medical University Eye Hospital, School of Optometry and Ophthalmology, Tianjin Medical University Eye Institute, Tianjin 300384, China

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Updated: July 27, 2021 — 1:03 am