Tag: Gene expression regulation

Analysis of differentially expressed genes and metabolic pathways in human uveal melanoma

Authors: Du Kuifang,  Xu Xiaolin,  Li Yang,  Wang Yingzhi,  Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2015.11.008 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 996-1003. Abstract                              [Download PDF] [Read Full Text] Background Studies showed that there exsits differential gene expression in human uveal melanoma […]

Negative regulation of exogeneous polyl-4-hydroxylase domain proteins on hypoxia-inducible factor pathway in human RPE cells

Authors: Ma Yu,  Tang Shaohua,  Jiang Yanrong,  Shi Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.03.009 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 234-238. Abstract                              [Download PDF] [Read Full Text] Background Anti-VEGF drugs are generally applied in the treatment of ocular neovascular diseases.However, the therapy effect is unsatisfactory […]

Expression changes of transforming growth factor-β1 and fibronectin in bovine trabecular meshwork cells cultured by iris pigment particles

Authors: Niu Chunhuan,  Wang Qiang,  Meng Jie,  Liu Yuzhen DOI: 10.3760/cma.j.issn.2095-0160.2017.04.008 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 320-324. Abstract                               [Download PDF] [Read Full Text] Background Pigmentary glaucoma and pseudoexfoliation glaucoma are characterized by pigment dispersion in trabecular meshwork, and the dipersitional pigment probably contributes to the […]

Inhibitory effects of microRNA-375 on biological behaviour of human retinal capillary endothelial cells induced by hypoxia

Authors: Zhu Jiang,  Ren Mei,  Xu Zhiguo DOI: 10.3760/cma.j.issn.2095-0160.2017.08.005 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 695-702. Abstract                              [Download PDF] [Read Full Text] Background Studies showed that microRNA (miR)-375 suppresses the growth, apoptosis, migration and adhesion of tumor cells, and it plays a regulation to the […]