Tag: genetic

Epigenetics, diseases and therapy in ophthalmology

Authors: Zhe Jing,  Xiaomeng Wu DOI: 10.3760/cma.j.issn.2095-0160.2015.08.001 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 673-677. Abstract                              [Download PDF] [Read Full Text] Heritable changes in gene expression are regarded as epigenetics, which do not involve coding sequence modifications. The study of […]

Clinical phenotype and maternal mutation analysis of Leber hereditary optic neuropathy

Authors: Huang Lyuzhen,  Li Tianqi,  Wang Bin,  Li Xiaoxin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.012 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 920-924. Abstract                              [Download PDF] [Read Full Text] Background Leber hereditary optic neuropathy (LHON) is a maternally inherited disease caused by mitochondrial DNA (mtDNA) mutation with the […]

Associations of single nucleotide polymorphisms of UCP genes with diabetic retinopathy in Chinese Han population

Authors: Jin Peiyao,  Li Zhiqiang,  Xu Xian,  He Jiangnan,  Chen Jianhua,  Xu Xun,  Du Xuan,  Bai Xuelin,  Zhang Bo,  He Xiangui,  Lu Lina,  Zhu Jianfeng,  Shi Yongyong,  Zou Haidong DOI: 10.3760/cma.j.issn.2095-0160.2017.08.015 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 737-742. Abstract                              [Download PDF] [Read Full Text] Background Researches showed that elevatory blood glucose level results in long-term damage […]