Authors: Zhe Jing, Xiaomeng Wu DOI: 10.3760/cma.j.issn.2095-0160.2015.08.001 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 673-677. Abstract [Download PDF] [Read Full Text] Heritable changes in gene expression are regarded as epigenetics, which do not involve coding sequence modifications. The study of […]
Category: 2015, No. 08
Modulation of MEK/ERK and PI3K/Akt pathways to the expression of DDR2 and MMP-13 in choroidal neovascularization
Authors: Yang Xiumei, Wang Yusheng, Zhang Jian, Li Yan, Yao Libo DOI: 10.3760/cma.j.issn.2095-0160.2015.08.002 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 678-685. Abstract [Download PDF] [Read Full Text] Background It is estimated that discoidin domain receptor 2 (DDR2) and matrix metalloproteinase-13 […]
Construction and assessment of recombinant plasmid pRNAT-U6.1/CFB siRNA and its inhibitory effect on proliferation of human umbilical vein endothelial cells
Authors: Tong Huan, Shang Qingli, Ma Jingxue, Gao Jian, Wang Xin DOI: 10.3760/cma.j.issn.2095-0160.2015.08.003 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 686-690. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is one of the causes of blindness in multiple […]
Change of serum response factor expression in eyelid of different embryo development stages of B6-Co mice
Authors: Song Hongyan, Li Yao, Lu Zeyan, Wu Liucheng, Shao Yixiang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.004 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 691-694. Abstract [Download PDF] [Read Full Text] Background Mutant C57BL/6 mouse with corneal opacity (B6-Co) appears eye open at birth […]
Promoting effect of connective tissue growth factor on expression of E-cadherin in human Tenon capsule fibroblasts
Authors: Li Jing, Xie Anming DOI: 10.3760/cma.j.issn.2095-0160.2015.08.005 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 695-698. Abstract [Download PDF] [Read Full Text] Background Scarring of filtration channel following glaucoma filtering surgery is a main cause of the failure of the surgery. […]
Next generation sequencing based molecular genetic analysis of a Chinese Han family with autosomal retinitis pigmentosa
Authors: Zhou Xiaomin, Huang Hui, Wang Ying, Wu Jing, Fan Ning, Jiang Shanming, Liu Xuyang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.006 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 699-703. Abstract [Download PDF] [Read Full Text] Background Retinitis pigmeutosa (RP) is a progressive inheritance disease. […]
Application of next-generation sequencing in detection of mutation gene in a Chinese pedigree with congenital cataract
Authors: Xiao Hai, Zhang Hui, Li Tao, Wu Dong, Zhang Chaoyang, Shi Weili, Qin Litao, Liao Shixiu DOI: 10.3760/cma.j.issn.2095-0160.2015.08.008 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 705-709. Abstract [Download PDF] [Read Full Text] Background Due to the genetic heterogeneity of […]
Detection of disease-causing gene in a Hui congential cataract pedigree by exon combined target region capture sequencing chip
Authors: Rong Weining, Zou Gang, Sheng Xunlun, Li Huiping, Zhang Fangxia DOI: 10.3760/cma.j.issn.2095-0160.2015.08.010 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 711-715. Abstract [Download PDF] [Read Full Text] Background Congenital cataract is an important cause of blindness and amblyopia in children, […]
Dynamic changes of retinal nerve fiber layer thickness and visual contrast sensitivity in young population with type 2 diabetes mellitus
Authors: Wang Wenying, Ji Xiangning, Han Fengmei, Zhang Xi, Li Kun DOI: 10.3760/cma.j.issn.2095-0160.2015.08.011 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 716-721. Abstract [Download PDF] [Read Full Text] Background In recent years, some researches show that getting younger over the diabetes […]
A recurrent mutation of CRYGD gene in a northern Chinese family with autosomal dominant congenital nuclear cataract
Authors: Zhang Xiaohui, Liu Weihua, Dong Bing, Chen Jieqiong, Li Yang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.012 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 722-726. Abstract [Download PDF] [Read Full Text] Background Congenital cataract is a major cause for blindness of childhood. Genetic […]