Tag: Glaucoma

Protective effect of NLRP12 knockdown on retinal damage in rats with ocular hypertension and its mechanism of inhibiting cell pyroptosis

Authors: Song Weiqiong,  He Fang,  Du Lingfang,  Tan Huaxia,  Liu Dan DOI: 10.3760/cma.j.cn115989-20211021-00572 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 110-118. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect and mechanism of NOD-like receptor family pyrin […]

Promoting effect of AGTR1 blocker olmesartan on the apoptosis of HTF and its mechanism

Authors: Wang Lijun,  Li Hongsong,  Zhang Wenyi,  Shao Meilin,  Ren Meimei,  Wang Jianming DOI: 10.3760/cma.j.cn115989-20220601-00262 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 119-126. Abstract                            [Download PDF] [Read Full Text] Objective To study the effect and mechanism of angiotensin type 1 […]

Advances in the study of exosomes in glaucoma diagnosis and treatment

Authors: Feng Xinting,  Zhang Xu DOI: 10.3760/cma.j.cn115989-20220429-00186 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 173-177. Abstract                               [Download PDF] [Read Full Text] Exosomes are small vesicles with nanoscale lipid bilayer structures, which are secreted by various cells and are widely […]

Research progress and prospect of metabonomics in glaucoma

Authors: Lu Yunqing,  Zhong Hua DOI: 10.3760/cma.j.cn115989-20200808-00572 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 178-182. Abstract                              [Download PDF] [Read Full Text] Metabonomics is an important component of systems biology.It reveals the essential metabolic characteristics of the activities of organisms […]

Research progress of cellular senescence in glaucoma

Authors: Ding Jianfeng,  Li Lu DOI: 10.3760/cma.j.cn115989-20200604-00394 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 183-187. Abstract                                [Download PDF] [Read Full Text] Cellular senescence is a response process in which cells are activated by ischemia, hypoxia, oxidative stress, DNA […]

Pressure-induced differentiation of rabbit retinal stem cells into retinal ganglion cells

Authors: Dai Min,  Kang Zefeng,  Hu Zhulin,  Li Yan DOI: 10.3760/cma.j.cn115989-20200519-00361 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1134-1140. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of pressure on the differentiation of rabbit retinal stem […]

Inhibitory effect of epigallocatechin gallate on human Tenon fibroblasts and its mechanism

Authors:  Chen Yanlei,  Lin Hongliang,  Wang Sheng,  Qin Yongjie,  Zhang Hongyang DOI: 10.3760/cma.j.cn115989-20211206-00672 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1023-1030. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of epigallocatechin gallate (EGCG) on the activation […]

New paradigms of immune regulation in glaucoma during the whole clinical process

Authors: Wu Jian,  Su Wenru,  Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20220314-00104 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 289-293. Abstract                              [View PDF] [Read Full Text] Glaucoma is an irreversible blinding eye disease caused by the structural and functional damage of optic nerve induced by pathological […]

Inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts

Authors: Wu Sharengaowa,  Cui Renzhe,  Lu Di,  Ding Haoxuan,  Sun Lixia DOI: 10.3760/cma.j.cn115989-20200609-00410 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 294-302. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human […]

Inhibitory effect of ILK-siRNA-AAV on scar formation after glaucoma filtering surgery in rats

Authors: Xing Yao,  Wang Jianming,  Fan Yazhi,  Xiong Lei,  Wang Wenjing,  Cui Lijun DOI: 10.3760/cma.j.cn115989-20210617-00362 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 316-325. Abstract                              [View PDF] [Read Full Text] Objective To investigate the role of integrin-linked kinase (ILK)-small interfering RNA (siRNA)-adeno-associated virus (AAV) […]