Category: 2017, No. 12

Rapid identification of pathogenic mutations in sporadic hereditary retinal dystrophies using targeted next-generation sequencing

Authors: Fang Xinhe,  Zhang Fangxia,  Zhu Yan,  Liu Yani,  Sheng Xunlun DOI: 10.3760/cma.j.issn.2095-0160.2017.12.009 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1097-1103. Abstract                              [Download PDF] [Read Full Text] Background Hereditary retinal diseases (HRDs) are a group of retinal degenerative diseases with significant genetic and clinical heterogeneities.Traditional techniques are challenging […]

Comparison in lens thickness and anterior chamber of early and intumescent stages of cataract by CASIA SS-1000 anterior segment optical coherence tomography

Authors: Hu Zongli,  Ye Jian DOI: 10.3760/cma.j.issn.2095-0160.2017.12.008 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1092-1096. Abstract                              [Download PDF] [Read Full Text] Background With the progression of cortical cataract, the lens thickness and anterior chamber will change and may have significant influences on the structure and […]

Inhibitory effects of bevacizumab on corneal neovascularization and scarring in mice with herpes simplex keratitis

Authors: Zhou Hongwei,  Wang Tongsong,  Zhang Songmei,  Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.007 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1085-1091. Abstract                               [Download PDF] [Read Full Text] Background Corneal neovascularization and inflammation occur in herpes simplex keratitis (HSK). Aciclovir (ACV) is an antiviral medication which is primarily used for […]

Lowing-intraocular pressure and improving aqueous humor dynamic effects of qingguangan drug granules in spontaneous glaucoma mice

Authors: Long Da,  Zhou Yasha,  Li Ping,  Liu Jiaqi,  Peng Jun,  Tan Hanyu,  Peng Qinghua  DOI: 10.3760/cma.j.issn.2095-0160.2017.12.006 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1079-1084. Abstract                              [Download PDF] [Read Full Text] Background Researches showed that the increase of intraocular pressure (IOP) in glaucomatous eye is associated with the increasing resistance […]

Expression changes and significance of ATP-binding cassette transporter B5 in pterygium

Authors: Cai Yan,  Zhao Xudong,  Wang Wei,  Yin Na,  Wang Huixian,  Gao Xiaowei DOI: 10.3760/cma.j.issn.2095-0160.2017.12.004 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1073-1077. Abstract                               [Download PDF] [Read Full Text] Background Limbal stem cells (LSCs) deficiency leads to many ocular surface diseases, such as pterygium and so on.ATP-binding cassette transporter […]

Regulation of sericin on retinal endoplasmic reticulum stress specific caspase-12 dependent pathway and inhibition on apoptosis in diabetic rat

Authors: Dong Zhijun,  Yang Nan,  Chen Zhihong,  Yang Fan,  Yu Hongfei,  Dong Weili,  Zhang Tiemin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.003 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1067-1072. Abstract                               [Download PDF] [Read Full Text] Background Endoplasmic reticulum stress (ERS) specific caspase-12 dependent pathway plays a key role in cell apoptosis, and apoptosis is […]

Activation of retinal and optic nerve microglia following optic nerve crush in rats

Authors: Nie Zuqing,  Zhang Qiong,  Cao Xia DOI: 10.3760/cma.j.issn.2095-0160.2017.12.002 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1060-1066. Abstract                               [Download PDF] [Read Full Text] Background Traumatic optic neuropathy (TON) is an acute injury of the optic nerve secondary to trauma.As an important immune cell, microglia is involved […]

Focusing on the methodology shift in epidemiological study of eye diseases

Authors: Zou Haidong DOI: 10.3760/cma.j.issn.2095-0160.2017.12.001 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1057-1059. Abstract                              [Download PDF] [Read Full Text] As chronic diseases gradually become the primary threat to the health of Chinese population and the rapid increase in the need of high eye health […]