Tag: Sprague-Dawley

The protactive effects and mechanisms of cx3cr1 antibody on retinal neuron in rats with ischemia reperfusion injury by intravitreal injection

Authors: Li Juanjuan,  Li Yan,  Tang Zhiwei  DOI: 10.3760/cma.j.issn.2095-0160.2016.01.007 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 35-41. Abstract                            [Download PDF] [Read Full Text] Background Study confirmed that the active microglia may injure retinal ganglion cells (RGCs) in retinal ischemia reperfusion injury (IRI), and increased cx3cr1 expression is […]

Contrast of retinal structure and function developing of premature rats versus full-term newborn rats

Authors: Yang Xiangmin,  Li Rong,  Wang Yusheng,  Su Jingbo,  An Jing,  Chen Tao,  Cao Qinglin,  Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2016.01.010 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 49-55. Abstract                            [Download PDF] [Read Full Text] Background Premature birth is a high risk factor of abnormal development in the morphology and function of vision system.To […]

Protective effect of miR-30b on retinal ganglion cells against oxygen-glucose deprivation in vitro

Authors: Huang Chanjuan,  Huo Yan,  Chen Chen,  Ai Liqianyu,  Zhou Yuanguo,  Ye Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.05.004 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 396-401. Abstract                            [Download PDF] [Read Full Text] Background Retinal ganglion cell (RGCs) death following ischaemic insult is the major cause of a number […]

Application of modified retinal flatmount combined with immunofluorescence staining in oxygen-induced retinopathy model

Authors:Li Rong,  Yao Guomin,  Wang Xiaodi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.005 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1077-1080. Abstract                              [Download PDF] [Read Full Text] Background Retinal flatmount of oxygen-induced retinopathy (OIR) animal models is a useful tool in the study of ischemic retinopathy.The retinas of OIR of rat or mouse […]

Inhibitory effects of jiajianzhujing decoction containing serum on proliferation of rat choroidal vascular endothelial cells

Authors:Liu Yanjiang,  Kang Zefeng,  Xing Kai,  Liu Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.12.003 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1065-1071. Abstract                              [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) of macular zone is one of blinding eye diseases.Conventional treatment methods include photodynamic therapy and intravitreal injection of anti-vascular endothelial growth […]

Protection of sericin to retinal microvessels and its mechanism in diabetic rats

Authors: Yu Hongfei,  Dong Zhijun,  Zhang Tiemin,  Yang Fan DOI: 10.3760/cma.j.issn.2095-0160.2017.01.007 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 32-37. Abstract                              [Download PDF] [Read Full Text] Background Diabetic retinopathy (DR) is a chronic inflammatory disease, with pathological changes of retinal microvessels.Studies demonstrated that sericin has anti-inflammation and anti-oxidation […]

Establishment of human scleral fibroblasts-seeded collagen matrix and its mechanical properties

Authors: Hu Shoulong,  Li Li,  Cui Dongmei,  Zeng Junwen DOI: 10.3760/cma.j.issn.2095-0160.2017.02.004 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 108-113. Abstract                              [Download PDF] [Read Full Text] Background Excessive elongation of axis and expansion of sclera is one of the hot topics in the study of the pathogenesis of […]

Aggravation effects of JAK-STAT signaling pathway in retinal ischemia reperfusion injury

Authors: Yang Le,  Shi Rui,  Shen Jiaquan,  Xue Yushun DOI: 10.3760/cma.j.issn.2095-0160.2017.08.004 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 690-694. Abstract                              [Download PDF] [Read Full Text] Background Retinal ischemia reperfusion injury (RIRI) is a common pathological process of many retinal vascular diseases with comprehensive pathogenesis mechanism.Researches showed that […]