Authors: Qiu Leyi, Yuan Huiping DOI: 10.3760/cma.j.cn115989-20241211-00346 Published: 2026 -03 -10 Citation Qiu Leyi, Yuan Huiping. Single-cell sequencing technology in exploring the role of microglia in glaucomatous optic nerve injury[J]. Chin J Exp Ophthalmol, 2026, 44(3):286-290. DOI: 10.3760/cma.j.cn115989-20241211-00346. ABSTRACT [Download PDF] [Read Full Text] Glaucoma is characterized by the progressive damage […]
Tag: Microglia
Role of intercellular communication involving microglia in retinal neurovascular unit
Authors: Lei Linyi, Cao Yuan, Yao Jin DOI: 10.3760/cma.j.cn115989-20230627-00025 Published: 2024-11-10 Citation Lei Linyi, Cao Yuan, Yao Jin. Role of intercellular communication involving microglia in retinal neurovascular unit[J]. Chin J Exp Ophthalmol, 2024, 42(11):1060-1064. DOI: 10.3760/cma.j.cn115989-20230627-00025 . ABSTRACT [Download PDF] [Read […]
Effect and mechanism of VSIG4 gene mutation on the function of microglia in retinitis pigmentosa
Authors: Xu Chunlong, Zhang Guowei, Du Jun, Jia Zhen, Wang Jingping, Wang Ziwen, Li Yang Lu Hong DOI: 10.3760/cma.j.cn115989-20240304-00063 Published： 2024 -10 -10 Citation: Xu Chunlong, Zhang Guowei, Du Jun, et al. Effect and mechanism of VSIG4 gene mutation on the function of microglia in retinitis pigmentosa[J]. Chin J Exp Ophthalmol, 2024, 42(10): 898-908. DOI: 10.3760/cma.j.cn115989-20240304-00063. ABSTRACT […]
Effect of microglia on photoreceptor in retina
Authors: Song Weilin, Yang Liu DOI: 10.3760/cma.j.cn115989-20200424-00284 Published 2024-08-10 Cite as Chin J Exp Ophthalmol, 2024, 42(8): 768-773. Abstract [Download PDF] [ Read Full Text] Microglia, the innate immune cells of the retina, can actively monitor changes […]
Research progression of Fractalkine/cx3cr1 and microglia in retina diseases
Authors: Li Juanjuan, Li Yan DOI: 10.3760/cma.j.issn.2095-0160.2015.09.021 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 861-864. Abstract [Download PDF] [Read Full Text] Fractalkine (Fkn) is the only member of CX3C subfamily of chemokine currently found, cx3cr1 is its specific receptor. Fkn/cx3cr1 […]
Inhibitory effect of gamma-secretase inhibitor on retinal neovascularization and regulative mechanism of Notch1 signal pathway
Authors: Cheng Zhixing, Xie Jie, Meng Qianli DOI: 10.3760/cma.j.cn115989-20220820-00384 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1031-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect and underlying mechanism of gamma-secretase inhibitor blocking Notch1 signaling on […]
Monitoring function of microglia in retina and nerve system diseases
Authors: Xu Jia, Jin Zibing DOI: 10.3760/cma.j.cn115989-20200918-00656 Published 2022-08-10 Cite asChin J Exp Ophthalmol, 2022, 40(8): 758-764. Abstract [View PDF] [Read Full Text] Microglia are the resident macrophages in the central nervous system (CNS), like Kupffer cells in the liver and dust […]
Role of retinal microglia-mediated parainflammation in age-related macular degeneration
Authors: Wang Yuwei, Li Jing DOI: 10.3760/cma.j.cn115989-20210922-00526 Published 2021-11-10 Cite asChin J Exp Ophthalmol, 2021, 39(11): 1021-1024. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is a disease caused by multiple factors such as age, genetics and environmental risks.Inflammation plays an important role […]
Protective effect and mechanism of cx3cr1 antibody intravitreal injection in microcirculation of retinal ischemia-reperfusion injury in mice
Authors: Li Juanjuan, Chen Chen, Li Yan, Zhang Liwei DOI: 10.3760/cma.j.cn115989-20200104-00004 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 585-592. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of C-X3-C motif chemokine receptor 1 (cx3cr1) antibody, a microglia activation inhibitor, […]
Current researches on effects of retinal neuroglial cells in glaucoma
Authors: Xue Bo, Ji Min, Guan Huaijin DOI: 10.3760/cma.j.issn.2095-0160.2016.07.016 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 649-653. Abstract [Download PDF] [Read Full Text] Glaucoma is a degenerative disease of the retina and the optic nerve.The apoptosis of retinal ganglion cells is the pathological basis […]