Category: 2018

Research progress in neuroregeneration of traumatic optic neuropathy

Authors: Chen Haiying,  Huang Zhengru DOI: 10.3760/cma.j.issn.2095-0160.2018.01.016 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 75-80. Abstract Traumatic optic neuropathy (TON) is commonly associated with blunt ocular trauma and craniofacial injuries, leading irreversible visual impairment.Like other mammalian mature central nerve system (CNS) neurons, retinal ganglion cell (RGC) is normally unable to regenerate axon spontaneously after optic […]

Advances in basic researches of pharmacological approachs of retinitis pigmentosa

Authors: Gao Qing,  Shen Yin DOI: 10.3760/cma.j.issn.2095-0160.2018.01.015 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 70-74. Abstract Retinitis pigmentosa (RP) is a hereditary ocular disease that can cause blindness.There is no effective treatment currently.Although new technologies, such as gene therapy, stem cell therapy, photogenetics and retinal prostheses have flourished in recent years, they have not been […]

Advances in the treatment of macular edema secondary to retinal vein occlusion

Authors: Chu Mengqi,  Shen Lijun DOI: 10.3760/cma.j.issn.2095-0160.2018.01.014 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 65-69. Abstract Retinal vein occlusion (RVO) is a common blinding retinal vascular disease, and the most important complication of vision loss is macular edema (ME). The main treatment for ME secondary to RVO was laser photocoagulation therapy previously, but some researches […]

Animal models of oxygen-induced retinopathy

Authors: Yang Ning,  Xing Yiqiao DOI: 10.3760/cma.j.issn.2095-0160.2018.01.013 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 61-64. Abstract Models of oxygen-induced retinopathy (OIR) have been built on several animals, including kitten, mouse, rat, rabbit, puppy and zebrafish.These models play an important role in studying the mechanisms and treatments of retinal neovascularization, which is partially mimicking the pathological […]

An effectiveness comparison of extensive and standard internal limiting membrane peeling for idiopathic macular hole with closed index less than 0.7

Authors: Wu Chao,  You Zhipeng DOI: 10.3760/cma.j.issn.2095-0160.2018.01.012 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 56-60. Abstract Objective To evaluate and compare the curative effects between extensive and standard internal limited membrane peeling (ILMP) during vitrectomy for idiopathic macular hole (IMH) with closed index<0.7 and provide an alternative basis for IMH. Methods The clinical data of […]

Surgical outcomes of 27-gauge vitrectomy for rhegmatogenous retinal detachment with air tamponade

Authors: Fang Dong,  Wei Yantao,  Zhang Zhaotian,  Dong Min,  Jiang Xintong,  Zhang Ting,  Zhou Xuezhi,  Chen Lu,  Peng Manjuan,  Zhang Shaochong  DOI: 10.3760/cma.j.issn.2095-0160.2018.01.011 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 51-55. Abstract Objective To evaluate the efficacy and safety of 27-gauge sutureless vitrectomy with air tamponade for rhegmatogenous retinal detachment (RRD). Methods The clinical data of 35 consecutive eyes with primary RRD from […]

Multi-mode imaging features of retinal arterial macroaneurysms

Authors: Dong Shuqian,  Li Qiuming DOI: 10.3760/cma.j.issn.2095-0160.2018.01.010 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 46-50. Abstract Objective To observe the clinical characteristics of multi-mode images of retinal arterial macroaneurysms and provide reference for the accurate diagnostic. Methods The clinic data of 24 patients (25 eyes) with retinal arterial macroaneurysms who were diagnosed in the First […]

Application of remote screening system for diabetic retinopathy in Beijing Desheng Community

Authors: Liang Shuting,  Cai Yi,  Bai Xiangli,  Tong Qizhe,  Deng Xun,  Shi Xuan,  Li Xiaoxin DOI: 10.3760/cma.j.issn.2095-0160.2018.01.009 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 40-45. Abstract Objective To develop a remote diabetic retinopathy (DR) screening system and to evaluate the effectiveness of the screening system in community. Methods A cross-sectional study was carried out under the informed consent of subjects […]

The effects of recombinant human platelet derived growth factor-BB on biological behaviours of human retinal vascular endothelial cells

Authors: Li Dan,  Liu Gaoqin,  Chen Lei,  Wang Mengjiao,  Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.008 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 34-39. Abstract Objective This study was to investigate the role of recombinant human platelet derived growth factor-BB(rhPDGF-BB) in the proliferation and migration of human retinal vascular endothelial cells (hRVECs). Methods hRVECs were cultured in DMEM with 10% fetal […]

Inhibitory effects of Genistein on hyperoxia-induced retinal neovascularization

Authors: He Ronghua,  Zhou Guohong,  Kong Li,  Li Chenyu DOI: 10.3760/cma.j.issn.2095-0160.2018.01.007 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 29-33. Abstract Objective To investigate the effect of Genistein, a tyrosinase inhibitor, on retinal neovascularization in mice. Methods Thirty-six 7-day-old C57BL/6J mice were randomly assigned into hyperoxia-induced group, Genistein group, DMSO group and normal control group.The mice in the […]