Authors: Chinese Hereditary Ocular Disease Diagnosis and Treatment Group, Chinese Hereditary Ocular Disease Alliance DOI: 10.3760/cma.j.cn115989-20230523-00188 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 833-842. Abstract 【Download PDF】 【Read Full Text】 Leber congenital amaurosis (LCA) is a group of early-onset hereditary […]
Tag: Gene therapy
Association between visual function and optic fiber layer thickness after gene therapy for Leber hereditary optic neuropathy
·Clinical Research· Association between visual function and optic fiber layer thickness after gene therapy for Leber hereditary optic neuropathy Yuan Jiajia1, Zhang Yong2, Chen Changzheng1, Yang Xueying1, Miao Qingmei1, Kai Yoon Fan3, Li Bin2,3 1Department of Ophthalmology, People’s Hospital of Wuhan University, Wuhan 430065, China; 2Department of Ophthalmology, Taihe Hospital, Hubei University of Medicine, Hubei, […]
Efficacy evaluation of intravitreal injection of rAAV2-ND4 gene for Leber hereditary optic neuropathy
·Clinical Research· Evaluation of the efficacy of rAAV2-ND4 intravitreal injection for Leber’s hereditary optic neuropathy Li Xin1, Tian Zhen1, Chen Zhang 1, Li Bin1 ,2 ,3, Zhang Yong 1 1Department of Ophthalmology, Shiyan Taihe Hospital, Affiliated Hospital of Hubei University of Medicine, Shiyan 442000, China; 2Department of Ophthalmology, Tongji Hospital, Tongji Medical College of Huazhong […]