Category: 2018, No. 07

Mutation analysis of the autosomal dominant Weill-Marchesani syndrome and genotype-phenotype review

2018, No. 07, Clinical Science

Authors: Li Jie,  Xing Yasi,  Li Zhanrong,  Qin Fangyuan,  Dai Shuzhen DOI: 10.3760/cma.j.issn.2095-0160.2018.07.006 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 514-518. Abstract                              [Download PDF] [Read Full Text] Objective To screen the disease-causing genes in an autosomal dominant(AD)Weill-Marchesani syndrome (WMS) family from Henan province in […]

Effects of long noncoding RNA-MIAT on lens epithelial to mesenchymal transition induced by transforming growth factor-β2

2018, No. 07, Experimental Science

Authors: Yue Xiujuan,  Su Sheng,  Wang Liyuan,  Lyu Jia,  Wang Lin,  Liu Ping DOI: 10.3760/cma.j.issn.2095-0160.2018.07.005 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 508-513. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the roles of long noncoding RNA-myocardial infarction-associated transcript (MIAT) on lens epithelial cells (LECs) fibrosis induced by […]

Expression dynamics of lens development-associated transcription factors in human embryonic stem cell-induced lentoid body

2018, No. 07, Experimental Science

Authors: Han Chenlu,  Wang Chunxiao,  Li Jinyan,  Luo Lixia DOI: 10.3760/cma.j.issn.2095-0160.2018.07.004 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 500-507. Abstract                              [Download PDF] [Read Full Text] Objective To observe the expression dynamics of lens-related transcription factors in human embryonic stem cell (hESC) differentiated into lentoid body(LB). Methods A […]

Changes of mitochondrial dynamics related genes expression in a glaucoma rat model

2018, No. 07, Experimental Science

Authors: Hu Xinxin,  Dai Yi,  Sun Xinghuai  DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]

Importance of genetic and preimplantation genetic diagnosis in the prevention and treatment of inherited pediatric oculopathies

2018, No. 07, Editorial

Authors: Chen Xue,  Zhao Chen DOI: 10.3760/cma.j.issn.2095-0160.2018.07.002 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 489-493. Abstract                              [Download PDF] [Read Full Text] Inherited pediatric oculopathies are a group of pediatric eye chiseases caused by genetic defects, and they are the primary causes […]