Tag: Lens epithelial cells

Inhibitory effect of indocyanine green on biological behavior and transdifferentiation of human lens epithelial cells and its mechanism

Authors: Liu Yajun,  Zhao Yingdi,  Zhang Wenwen,  Zhang Si,  He Zifang,  Chen Feifei,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20220817-00380 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1160-1168. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of indocyanine […]

Inhibitory effect of astaxanthin on oxidative stress damage in lens epithelial cells and its mechanism

Authors: Li Yong,  Liu Zhaochen,  Peng Huacong DOI: 10.3760/cma.j.cn115989-20200624-00448 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 428-435. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the regulatory effect of astaxanthin on oxidative stress injury induced by hydrogen peroxide […]

Establishment of lens opacity model in Grx2 knockout mice based on CRISPR/cas9 system and the role of Grx2 in the pathogenesis of cataract

·Experimental Research· Establishment of a lens opacity model in Grx2 knockout mice based on the CRISPR/cas9 system and the role of Grx2 in cataract pathogenesis Guo Yong1, Guo Chenjun2, Zhang Jie2, Ning Xiaona2, Chen Xi3, Yan Hong1 1Department of Ophthalmology, Xi’an People’s Hospital, Xi’an Fourth Hospital, Shaanxi Eye Hospital, Xi’an 710004, China; 2Department of Ophthalmology, […]

Inhibitory effect of microRNA-23b-3p on high glucose-induced autophagy and apoptosis of human lens epithelial cells and its mechanism

·Experimental Research· Role and mechanism of microRNA-23b-3p in regulating high glucose-induced autophagy and apoptosis of human lens epithelial cells Liu Wenlan, Wang Li, Yang Yang, Yan Jin School of Medical Technology, Xi’an Medical University, Xi’an 710021, China Corresponding author: Wang Li, Email: 63148645@qq.com [Abstract]                        […]

Inhibition of lens epithelial cell migration using different square-edge intraocular lenses in an in vitro capsular bag model

Authors: Lian Feiyue,  Li Yang,  Jiang Lingfeng,  Shen Haoyue,  Zhao Jiangyue,  Yan Xiaoxiao,  Yu Jiaming,  Qin Yu DOI: 10.3760/cma.j.cn115989-20200514-00346 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 395-402. Abstract                              [View PDF] [Read Full Text] Objective To establish an in vitro […]

Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1

Authors: Niu Yantao,  Zhang Li,  Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract                              [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]

Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism

·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract                  […]

Research progress of correlation between microRNA and the pathogenesis of cataract

Authors: Pu Yadi,  Li Yuanbin DOI: 10.3760/cma.j.cn115989-20200413-00255 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 475-480. Abstract                              [View PDF] [Read Full Text] MicroRNA (miRNA) is a kind of small non-coding RNA, which can specifically bind to the 3′ untranslated region of the target RNA, […]