Tag: Animal models

Research progress on the pathogenesis and animal models of pachychoroid spectrum disorders

Authors: Li Shaoheng, Wang Yusheng, Su Yuting DOI: 10.3760/cma.j.cn115989-20241014-00288 Published: 2026 -01 -10 Citation Li Shaoheng, Wang Yusheng, Su Yuting. Research progress on the pathogenesis and animal models of pachychoroid spectrum disorders[J]. Chin J Exp Opthalmol, 2026, 44(1):61-66. DOI: 10.3760/cma.j.cn115989-20241014-00288. ABSTRACT               [Download PDF]  [Read Full Text] Pachychoroid spectrum disorders […]

Expert consensus on diagnosis and treatment of achromatopsia in China (2025)

Authors: Chinese Hereditary Ocular Disease Diagnosis and Treatment Group, Chinese Hereditary Ocular Disease Alliance, Expert Workgroup of Expert consensus on diagnosis and treatment of achromatopsia in China (2025) DOI: 10.3760/cma.j.cn115989-20250429-00140 Published: 2025 -10 -10 Citation Chinese Hereditary Ocular Disease Diagnosis and Treatment Group, Chinese Hereditary Ocular Disease Alliance, Expert Workgroup of Expert consensus on diagnosis and treatment of achromatopsia […]

Digital measurement of corneal curvature and eccentricity of guinea pigs using Python

Authors: Di Yue,  Li Xinyue,  Fang Wangyi,  Huang Ying,  Luo Wenting,  Ye Haiyun,  Qiao Zhongbao,  Qiao Tong DOI: 10.3760/cma.j.cn115989-20220727-00349 Published 2023-08-10 Cite as Chin J Exp Ophthalmol, 2023, 41(8): 724-729. Abstract                               [Download PDF] [Read Full Text] Objective To investigate an accurate and […]

Value of virtual operating system for visual behavioral assessment in mice models of visual disease

Authors: Jiao Yang,  Shao Zhengbo DOI: 10.3760/cma.j.cn115989-20210524-00315 Published 2023-08-10 Cite as Chin J Exp Ophthalmol, 2023, 41(8): 822-826. Abstract                               [Download PDF] [Read Full Text] Visual behaviorally operant method is one of the main detections for identifying animal models of visual diseases, which […]

Inhibitory effects of 1% atropine on form deprivation-induced myopia development in guinea pigs and its mechanism

Authors: Ji Xiaowen,  Gong Boteng,  Zhu Ying,  Lu Daqian,  Liu Lin,  Du Bei,  Liu Xun,  Wei Ruihua DOI: 10.3760/cma.j.cn115989-20211026-00584 Published 2023-04-10 Cite as Chin J Exp Ophthalmol, 2023, 41(4): 303-311. Abstract                              [Download PDF] [Read Full Text] Objective To observe the prevention and […]

Screening, identification and functional analysis of differential expression genes in rat visual cortex after monocular deprivation by RNA-Seq technique

Authors: Sun Yaling,  Yan Xingke,  Liu Anguo DOI: 10.3760/cma.j.cn115989-20201106-00750 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 210-215. Abstract                              [View PDF] [Read Full Text] Objective To screen differentially expressed genes (DEGs) in rat visual cortex after monocular deprivation by RNA sequencing technology, and to […]

Changes of mitochondrial dynamics related genes expression in a glaucoma rat model

Authors: Hu Xinxin,  Dai Yi,  Sun Xinghuai  DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]

Dry eye animal models and dry eye drug development

Authors: Wang Weizhuo,  Chen Miao,  Lingyun Cheng DOI: 10.3760/cma.j.issn.2095-0160.2018.12.012 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 956-961. Abstract                              [Download PDF] [Read Full Text] Dry eye is the most common eye illness which manifests as a chronic inflammation on ocular surface and imposes […]