Tag: Posterior capsule opacification

Suppressing effects of MMPs inhibitor GM6001, MMP-2/9 inhibitorⅠ, MMP-2/9 inhibitorⅡ on migration of human lens epithelial cells

Authors: Liu Dongmei,  Li Junhong DOI: 10.3760/cma.j.issn.2095-0160.2015.09.009 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 811-815. Abstract                              [Download PDF] [Read Full Text]  Background The primary pathologic mechanism of posterior capsular opacification (PCO) is proliferation, migration and epithelial-mesenchymal transformation of residuary lens […]

Inhibitory effect of siRNA-Pax6 on biological behavior and epithelial-mesenchymal transition of human lens epithelial cells

Authors: Zheng Yuxing,  Yang Xiaoxi,  Yi Guoguo,  Wu Shuduan,  Feng Zhizhen,  Xia Zhaoxia DOI: 10.3760/cma.j.cn115989-20210423-00272 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 499-506. Abstract                                       [View PDF]  [Read Full Text] Objective To explore the effect of […]

Research and prospect of inhibitors of mammalian target of rapamycin signaling pathway on the prevention and treatment of posterior capsule opacification

Authors:Chen Jiayu,  Liu Hongling DOI: 10.3760/cma.j.cn115985-20190923-00411 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 360-364. Abstract                              [View PDF] [Read Full Text] Posterior capsule opacification (PCO) is the most common complication of extracapsular cataract extraction and intraocular lens implantation in the long-term.After […]

Assessment of posterior capsule penetrability by Pentacam Scheimpflug system

Authors: Cao Qianzhong,  Tian Zhen,  Chen Qian,  Liu Yizhi DOI: 10.3760/cma.j.issn.2095-0160.2016.03.014 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 260-264. Abstract                            [Download PDF] [Read Full Text] Background Posterior capsule opacification (PCO) is a common complication following cataract surgery.Establishing an objective morphological evaluation method of PCO is of important clinical […]

Inhibition effects of sulforaphane-induced autophagy flux to cell proliferation on ex vivo human capsular bags

Authors: Liu Hanruo,  Yuan Bowei,  An Ying,  Wan Xiuhua DOI: 10.3760/cma.j.issn.2095-0160.2017.03.009 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 226-232. Abstract                              [Download PDF] [Read Full Text] Background Sulforaphane (SFN) is an effective chemopreventive agent and can regulate the biological molecular mechanisms to inhibit the overgrowth of cells.Autophagy is […]

Application of RNA interference in posterior capsule opacification by interfering signaling pathway

Authors: Xi Yahui,  Liu Hongling DOI: 10.3760/cma.j.issn.2095-0160.2017.12.014 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1126-1129. Abstract                              [Download PDF] [Read Full Text] Posterior capsule opacification (PCO) is a common complication after cataract phacoemulsification with intraocular lens (IOL) implantation.The mechanism of lens epithelial […]

Effects of long noncoding RNA-MIAT on lens epithelial to mesenchymal transition induced by transforming growth factor-β2

Authors: Yue Xiujuan,  Su Sheng,  Wang Liyuan,  Lyu Jia,  Wang Lin,  Liu Ping DOI: 10.3760/cma.j.issn.2095-0160.2018.07.005 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 508-513. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the roles of long noncoding RNA-myocardial infarction-associated transcript (MIAT) on lens epithelial cells (LECs) fibrosis induced by […]