Category: 2018, No. 10

Mitochondrial damage and related ocular disorders

Authors: Chen Qiang,  Liang Lina DOI: 10.3760/cma.j.issn.2095-0160.2018.10.017 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 812-816. Abstract Mitochondria are recognized to function as the powerhouse of the cell.The etiology of many common ocular disorders is increasingly recognized to involve either an accumulation of mitochondrial DNA (mtDNA) mutations and/or secondary mitochondrial damage.Novel pathogenic mtDNA mutations continue to […]

Progress in research of nicotinamide adenine dinucleotide imbalance mediated retinal neurodegeneration

Authors: Liu Yang,  Luo Xueting DOI: 10.3760/cma.j.issn.2095-0160.2018.010.016 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 808-811. Abstract Nicotinamide adenine dinucleotide (NAD+ ) is a critical mediator in biochemical reactions.It serves both as a coenzyme in reduction-oxidation reactions, and as a cosubstrate for other enzymes in molecular signal transduction.The homeostasis of intracellular synthesis and consumption of NAD+ […]

Development status and future challenges of ocular surgical robot

Authors: Lin Duoru,  Huang Kai,  Lin Haotian DOI: 10.3760/cma.j.issn.2095-0160.2018.10.015 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 804-807. Abstract Surgical robots have the advantages of good flexibility, high precision and stable operation, which is an important way to improve the safety and accuracy of ophthalmic surgical operations.Scholars have carried out preliminary explorations on the application of robots […]

Tear components in thyroid associated ophthalmopathy

Authors: Fan Xiaotian,  Wei Ruili DOI: 10.3760/cma.j.issn.2095-0160.2018.10.014 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 800-803. Abstract Thyroid associated ophthalmopathy (TAO) is the most common autoimmune inflammatory orbital disease in adults.Because of its high incidence and the threat of vision, early detection and diagnosis is critical.Proteomics of tear fluid in TAO patients demonstrates that up-regulation of […]

Application of artificial intelligence in ocular imaging diagnosis

Authors: Wang Shasha,  Chen Jili DOI: 10.3760/cma.j.issn.2095-0160.2018.10.013 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 796-799. Abstract In ophthalmic clinical, a variety of image-related techniques are used to analyze the patient’s condition, help the diagnosis and guide the prognosis.The artificial intelligence is based on computer intelligence science, which has great advantages in image recognition and gradually […]

Progress of GNAQ/GNA11 mutation in uveal melanoma

Authors: Zheng Lei,  Zhang Guoming DOI: 10.3760/cma.j.issn.2095-0160.2018.10.012 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 791-795. Abstract Uveal melanoma (UM) is the most common primary intraocular tumor in adults, which not only affects patients’ visual function, but easily leads to death.Despite the advance in local treatments of UM, there has been no change in patients’ survival […]

Clinical features of cancer-associated retinopathy

Authors: Li Hui,  Yang Lizhu,  Zou Xuan,  Sun Zixi,  Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2018.10.011 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 786-790. Abstract Objective To analyze the clinical features of cancer-associated retinopathy (CAR). Methods The clinical data of 10 patients who diagnosed as CAR during 5 years were retrospectively analyzed.All patients underwent detailed ocular examinations, including electroretinogram (ERG), optical […]

Clinical etiological analysis of severe vitreous hemorrhage in venerable age patients

Authors: Wang Yenan,  Hu Yuntao,  Ma Zhizhong,  Wang Changguan,  Dou Hongliang,  Feng Xuefeng,  Xu Yimin,  Wang Xizhe DOI: 10.3760/cma.j.issn.2095-0160.2018.10.009 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 780-784. Abstract Objective To analyze the etiologies of severe vitreous hemorrhage in venerable age patients. Methods A retrospective series case study was adopted.Medical records of 30 cases 30 eyes severe vitreous hemorrhage venerable age patients […]

Analysis of genetic susceptibility to proliferative diabetic retinopathy in Han patients with type 2 diabetes from Southern China by whole exome sequencing and SnaPshot

Authors: Xie Jie,  Jiang Zhengxuan,  Zhang Liang,  Cui Ying,  Wang Jun,  Zhang Aiping,  Meng Qianli DOI: 10.3760/cma.j.issn.2095-0160.2018.10.008 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 774-779. Abstract Objective To research the genetic susceptibility of proliferative diabetic retinopathy (PDR) in Han patients with type 2 diabetes from Southern China. Methods A cross-sectional study was performed under the informed consent of the patients.Patients […]

Pulsed and continuous accelerated scleral cross-linking using riboflavin and ultraviolet A irradiation for the prevention of myopia progression in a guinea pig model

Authors: Xu Haiming,  Liu Hui,  Yu Jie,  He Jinjing DOI: 10.3760/cma.j.issn.2095-0160.2018.10.006 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 767-772. Abstract Objective To evaluated the effect of oral administration of riboflavin combined with pulsed and continuous light accelerated scleral cross-linking on the histological and biomechanical properties of sclera in a guinea pig model to control the progression of […]