Authors: Jiang Bo, Lu Peirong DOI: 10.3760/cma.j.cn115989-20210419-00265 Published: 2024 -09 -10 Citation: Jiang B, Lu PR. Application of single-cell RNA sequencing in the study of ophthalmologic diseases[J]. Chin J Exp Ophthalmol,2024,42(9):852-857. DOI: 10.3760/cma.j.cn115989-20210419-00265. ABSTRACT [Download PDF] [Read Full Text] Single-cell RNA sequencing (scRNA-seq) is a powerful and rapidly developing emerging technology that allows complete analysis of […]
Tag: RNA sequencing
Transcriptomics analysis of hypoxia-induced retinal pigment epithelium cell injury
Authors: Lu Cong, Shi Pingling, Yang Qixiang, Song Hao, Li Miao, Zhang Beibei, Song Zongming DOI: 10.3760/cma.j.cn115989-20201127-00799 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 505-514. Abstract [View PDF] [Read Full Text] Objective To analyze differentially expressed genes (DEGs) and the changes of signal […]
Differential gene expression profiles of trabecular meshwork between POAG and non-POAG donated eyes by using RNA-sequencing
Authors: Liu Lifang, Zeng Jinhui, Huang Chukai, Wang Geng, Zhang Mingzhi DOI: 10.3760/cma.j.cn115989-20191018-00451 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 646-652. Abstract [View PDF] [Read Full Text] Objective To investigate gene basis of primary open angle glaucoma (POAG) by comparing gene expression profile of […]
Application of single-cell RNA sequencing in visual system
Authors: Liu Yifan, Shen Yin DOI: 10.3760/cma.j.cn115989-20200509-00325 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 704-709. Abstract [View PDF] [Read Full Text] Single-cell RNA sequencing (scRNA-seq) is an emerging technology that observes transcriptomes’ differences between individual cells at the cellular level.The basic strategy is to […]
Differentially expressed genes analysis of retinal vascular endothelial cells under hyperglycemia and hyperlipidemia induced by α-melanocyte-stimulating hormone
Authors:Wu Mianmian, Guo Fang, Li Yahong, Liu Ke, Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2019.09.002 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 694-700. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of α-melanocyte-stimulating hormone(α-MSH) on the expression of mRNA and long noncoding RNA (lncRNA) […]
Analysis of differentially expressed genes of Staphylococcus aureus isolated from corneal ulcer and healthy conjunctival sac
Authors:Liu Qing, Dong Yanling, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2019.09.003 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 701-706. Abstract [View PDF] [Read Full Text] Objective To investigate the possible pathogenesis of Staphylococcus aureus (S.aureus) corneal ulcer by analyzing the differentially expressed genes (DEGs) of S.aureus isolated from the patients with […]