Tag: CRISPR-Cas systems

Application of CRISPR/Cas9 gene editing technology in the construction of animal models of ophthalmic diseases

Authors: Ma Xiaochen,  Liu Hongling DOI: 10.3760/cma.j.cn115989-20190930-00425 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 972-975. Abstract                                       [View PDF] [Read Full Text]  The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated endonuclease 9 (Cas9) technology is a gene editing technology that uses […]

Applications of CRISPR/Cas9 genome editing technology in gene therapy for hereditary eye diseases

Authors:  Wu Shijing,  Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2018.11.016 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 892-896. Abstract                               [Download PDF] [Read Full Text] Clustered regulatory interspaced short palindromic repeat (CRISPR)/CRISPR associated nuclease (Cas) system is an adaptive immune system that confers resistance to exogenous virus or plasmid […]