Tag: Animal model

Review of methods for establishing limbal stem cell deficiency in animal model

Authors: Guo Xiaoxiao,  Li Xinyu DOI: 10.3760/cma.j.cn115989-20211130-00660 Published 2024-02-10 Cite as Chin J Exp Ophthalmol, 2024, 42(2): 202-208. Abstract                            【Read Full Text】【Download PDF】 Limbal stem cell deficiency (LSCD) is a common ocular surface disease.Severe LSCD can cause irreversible vision loss and the only […]

Application of CRISPR/Cas9 gene editing technology in the construction of animal models of ophthalmic diseases

Authors: Ma Xiaochen,  Liu Hongling DOI: 10.3760/cma.j.cn115989-20190930-00425 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 972-975. Abstract                                       [View PDF] [Read Full Text]  The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated endonuclease 9 (Cas9) technology is a gene editing technology that uses […]

Advances in rodent models of retinal neovascularization

Authors: Xu Qianhui,  Chen Jun,  Shao Yi DOI: 10.3760/cma.j.cn115989-20200211-00064 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 996-998. Abstract                                       [View PDF]  [Read Full Text]  Retinal neovascularization (RNV) originating from retinal blood vessels is one of the main pathological features of many ocular […]