Authors: Zhang Jiaxun, He Yuxi, Zhang Yan DOI: 10.3760/cma.j.cn115989-20220930-00464 Published: 2025 -04 -10 Citation Zhang Jiaxun, He Yuxi, Zhang Yan. Research progress in animal models of allergic conjunctivitis[J]. Chin J Exp Ophthalmol, 2025, 43(4):378-384. DOI: 10.3760/cma.j.cn115989-20220930-00464. [Download PDF] [View Full Text] ABSTRACT Allergic conjunctivitis has a high incidence rate, which is difficult to cure after repeated attacks, and […]
Tag: Animal model
Review of methods for establishing limbal stem cell deficiency in animal model
Authors: Guo Xiaoxiao, Li Xinyu DOI: 10.3760/cma.j.cn115989-20211130-00660 Published 2024-02-10 Cite as Chin J Exp Ophthalmol, 2024, 42(2): 202-208. Abstract 【Read Full Text】【Download PDF】 Limbal stem cell deficiency (LSCD) is a common ocular surface disease.Severe LSCD can cause irreversible vision loss and the only […]
Research progress of Leber hereditary optic neuropathy
Authors: Zhang Yangyang, Pang Jijing DOI: 10.3760/cma.j.issn.2095-0160.2015.08.018 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 755-759. Abstract [Download PDF] [Read Full Text] Leber hereditary optic neuropathy (LHON) is one of the most common maternally transmitted hereditary retinal diseases, which is […]
Application of CRISPR/Cas9 gene editing technology in the construction of animal models of ophthalmic diseases
Authors: Ma Xiaochen, Liu Hongling DOI: 10.3760/cma.j.cn115989-20190930-00425 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 972-975. Abstract [View PDF] [Read Full Text] The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated endonuclease 9 (Cas9) technology is a gene editing technology that uses […]
Advances in rodent models of retinal neovascularization
Authors: Xu Qianhui, Chen Jun, Shao Yi DOI: 10.3760/cma.j.cn115989-20200211-00064 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 996-998. Abstract [View PDF] [Read Full Text] Retinal neovascularization (RNV) originating from retinal blood vessels is one of the main pathological features of many ocular […]
Establishment and evaluation of a novel retinal ischemia-reperfusion injury model
Authors: Wen Xin, Yuan Miner, Li Cheng, Zeng Jieting, Lin Xiaofeng DOI: 10.3760/cma.j.cn115989-20190404-00162 Published 2020-07-10 Cite as Chin J Exp Ophthalmol, 2020,38(07): 566-572. Abstract [View PDF] [Read Full Text] Objective To explore the feasibility to establish a novel retinal ischemia reperfusion (RIR) injury model by applying […]
Advances in animal models of retinal vein occlusion induced by laser photocoagulation and photodynamic therapy
Authors: Pei Chao, Feng Jun DOI: 10.3760/cma.j.cn115985-2019-0409-00174 Published 2020-07-10 Cite as Chin J Exp Ophthalmol, 2020,38(07): 621-624. Abstract [View PDF] [Read Full Text] Retinal vein occlusion (RVO) is a common retinal vascular disease that causes vision loss.The etiology of RVO is complex and its pathogenesis has […]
Inhibitory effect of scleral crosslinking using genipin on form-deprivation myopia in rabbits
Authors: Zhao Yafang, Xu Yincong, Wang Chaoying, Song Honglu DOI: 10.3760/cma.j.issn.2095-0160.2019.12.006 Published 2019-12-10 Cite as Chin J Exp Ophthalmol, 2019,37(12): 962-966. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of scleral crosslinking using genipin on ocular biological parameters and scleral biomechanics of form-deprivation […]
Relationship between autophagy and retinal ganglion cells in animal models of glaucoma
Authors: Fu Shiya, Zhang Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.02.018 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 180-183. Abstract [Download PDF] [Read Full Text] The main pathological feature of glaucoma is progressive loss of retinal ganglion cells (RGCs), and the damage mechanisms have not been elucidated.Autophagy is a […]
Paying attention to the differences and applications of animal models of diabetic retinopathy
Authors: Chen Danian, Wang Yujiao DOI: 10.3760/cma.j.issn.2095-0160.2018.06.002 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 404-409. Abstract [Download PDF] [Read Full Text] Diabetic retinopathy (DR) is a common complication of diabetes, and remains the leading cause of blindness among working-age individuals all over the world.Current treatments […]