Tag: Differentiation

Advances in differentiation of human embryonic stem cells into corneal endothelial cells under the mimical microenvironment

Authors: Sun Lin,  Wu Xinyi DOI: 10.3760/cma.j.issn.2095-0160.2015.09.017 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 844-847. Abstract                              [Download PDF] [Read Full Text] The lack of donor corneal endothelium is a serious impediment to the development of corneal endothelial transplantation, whereas the […]

Construction of tissue-engineered corneal epithelium by culturing human amniotic mesenchymal stem cells in vitro

Authors: Xiao Pan,  Chen Jian DOI: 10.3760/cma.j.issn.2095-0160.2015.11.007 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 991-995. Abstract                                [Download PDF] [Read Full Text] Background  Corneal transplantation is an effective treatment to severe corneal diseases, but the shortage of cornea donor limits […]

The pilot study on rapamycin retarding the differentiation of RPE cells in vitro

Authors: Jiang Chao,  Zhao Chen,  Shi Houxia,  Ding Sijia DOI: 10.3760/cma.j.issn.2095-0160.2015.12.003 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1064-1068. Abstract                             [Download PDF] [Read Full Text] Background Retinal pigment epithelial (RPE) cell transplantation is a novel approach to the treatment of hereditary […]

Generation of VSX2 fluorescent reporter human induced pluripotent stem cells by CRISPR/Cas9 technology

Authors: Zheng Dandan,  Wang Yuan,  Zhang Zuming,  Guan Yuanyuan,  Xie Bingbing,  Jin Kangxin,  Xiang Mengqing,  Zhong Xiufeng DOI: 10.3760/cma.j.cn115989-20200729-00535 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 814-820. Abstract                               [View PDF] [Read Full Text] Objective To establish a fluorescent reporter human induced pluripotent stem […]

Evaluation of the retinal differentiation ability of human induced pluripotent stem cells reprogrammed from different somatic cells

Authors: Xie Bingbing,  Guan Yuanyuan,  Gao Guanjie,  Zheng Dandan,  Xu Ping,  Song Xiaojing,  Zhong Xiufeng DOI: 10.3760/cma.j.cn115989-20200805-00563 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 821-827. Abstract                              [View PDF] [Read Full Text] Objective To evaluate the retinal differentiation ability of human induced pluripotent stem […]

The features of in vivo laser confocal microscope images of frequent fungal keratitis

Authors: Xia Yuan,  Xue Chunyan,  Wu Yan,  Huang Zhenping DOI: 10.3760/cma.j.issn.2095-0160.2016.02.013 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 155-159. Abstract                              [Download PDF] [Read Full Text] Background Fungal keratitis is one of primary infectious ocular diseases in China. Conventional diagnostic method is fungal cultivation. In vivo laser confocal […]

Advance in methods of induced-embryonic stem cell differentiation to retinal cells

Authors: Zhao Yongji,  Pang Li,  You Zhipeng DOI: 10.3760/cma.j.issn.2095-0160.2016.09.016 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 851-854. Abstract                              [Download PDF] [Read Full Text] Retinal degenerative disease is the leading cause of visual loss, the mechanism is not clear and has no effective […]

The effect of tanshinone on meibomian gland cell proliferation, differentiation and lipid synthesis

Authors: Lai Qinghua,  Gao Yingying,  Li Wei,  Zuo Chengyou,  Li Qingmin DOI: 10.3760/cma.j.issn.2095-0160.2019.06.006 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 432-438. Abstract                               [View PDF] [Read Full Text] Objective To investigate the effects of cryptotanshinone and tanshinone ⅡA, two major monomer components of tanshinone, on the proliferation, differentiation and […]