Authors:Wang Qing, Zhuang Tongtong, Dong Lijie,Wang Linni Corresponding author:Wang Linni, Email:wln5156@163.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20250609-00190 ABSTRACT Objective To observe the effect and possible mechanism of interleukin (IL)-8 antagonist SB225002 on the activation of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in monkey retinal vascular endothelial cells (RF/6A cells) under high glucose conditions. Methods The RF/6A cells cultured in vitro were […]
Tag: Inflammasome
Research progress of nucleotide-binding oligomerzation domain like receptors 3 inflammasome in age-related macular degeneration
Authors: Sun Mengsha, Yan Quan, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.017 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 316-320. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is a multifactorial neurodegenerative disease characterized by the deterioration of the macula resulting in impaired […]
Research progress of nucleotide-binding oligomerzation domain like receptors 3 inflammasome in age-related macular degeneration
Authors: Sun Mengsha, Yan Quan, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.017 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 316-320. Abstract Age-related macular degeneration (AMD) is a multifactorial neurodegenerative disease characterized by the deterioration of the macula resulting in impaired visual acuity, which could probably cause irreversible vision loss.The pathogenesis of AMD is not clear yet though it has […]