Authors:Wang Qing, Zhuang Tongtong, Dong Lijie,Wang Linni Corresponding author:Wang Linni, Email:wln5156@163.com Published:2026-07-10 DOI: 10.3760/cma.j.cn115989-20250609-00190 ABSTRACT Objective To observe the effect and possible mechanism of interleukin (IL)-8 antagonist SB225002 on the activation of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in monkey retinal vascular endothelial cells (RF/6A cells) under high glucose conditions. Methods The RF/6A cells cultured in vitro were divided into […]
Tag: Nucleotide-binding oligomerization domain-like receptor protein 3
Role of NLRP3 inflammasome signaling pathway in the occurrence and development of diabetic keratopathy
Authors: Wan Luqin, Zhou Qingjun, Xie Lixin DOI: 10.3760/cma.j.cn115989-20190618-00266 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 680-684. Abstract [View PDF] [Read Full Text] Diabetic keratopathy is a chronic complication of diabetes caused by abnormal metabolites accumulation, oxidative stress, abnormal inflammation […]