Tag: Retinal vascular endothelial cells

Inhibitory effect and mechanism of SB225002 on NLRP3 inflammasome in retinal vascular endothelial cells under high glucose

Authors:Wang Qing, Zhuang Tongtong, Dong Lijie,Wang Linni Corresponding author:Wang Linni, Email:wln5156@163.com Published:2026-07-10 DOI:10.3760/cma.j.cn115989-20250609-00190 ABSTRACT  Objective To observe the effect and possible mechanism of interleukin (IL)-8 antagonist SB225002 on the activation of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in monkey retinal vascular endothelial cells (RF/6A cells) under high glucose conditions. Methods The RF/6A cells cultured in vitro were […]

Inhibitory effect of miR-146a on high glucose-induced apoptosis of retinal microvascular endothelial cells and its mechanism

Authors:  Gao Fei,  Wu Zhipeng,  Ruan Yihua DOI: 10.3760/cma.j.cn115989-20190703-00286 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 398-403. Abstract                               [View PDF] [Read Full Text] Objective To investigate the effect of microRNA-146a (miR-146a) on apoptosis of human retinal microvascular endothelial cells (HRMECs) induced by high […]

The promoting effects of insulin-like growth factor 1 on the biological behaviour of human retinal vascular endothelial cells

Authors: Wang Mengjiao,  Liu Gaoqin,  Xu Jing,  Li Dan,  Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.007 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 417-422. Abstract                               [Download PDF] [Read Full Text] Background The suppression of retinal angiogenesis is one of primary treatment targets for retinal vascular diseases, so seeking the intervention targets […]