Tag: NLRP3 inflammasome

Inhibitory effect of melatonin on pyroptosis of lens epithelium cells and its mechanism

Authors: Yang Xin,  Liu Xuhui,  Meng Jia,  Fang Mengyuan,  Zhang Fengyan DOI: 10.3760/cma.j.cn115989-20210516-00307 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 414-421. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of melatonin on pyroptosis of lens epithelium cells (HLECs) induced […]

Inhibitory effect of rosmarinic acid on high glucose-induced angiogenesis of human retinal microvascular endothelial cells and the activation of NLRP3 inflammasome pathway

Authors: Fan Jiangli,  Guan Yanling,  Li Rong,  Yao Yang DOI: 10.3760/cma.j.cn115989-20191203-00520 Published 2021-11-10 Cite asChin J Exp Ophthalmol, 2021, 39(11): 940-948. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effects of rosmarinic acid (RA) on high glucose-induced angiogenesis of human retinal microvascular […]