Tag: High glucose

Antagonistic effect of SC79 on high glucose-induced apoptosis of RPE cells and its regulatory mechanism on AKT-XIAP signaling pathway

Authors: Zheng Lei,  Ma Dahui,  Chen Miaohong,  Zhang Guoming DOI: 10.3760/cma.j.cn115989-20210710-00405 Published 2023-03-10 Cite as Chin J Exp Ophthalmol, 2023, 41(3): 226-232. Abstract                               [Download PDF]  [Read Full Text] Objective To investigate the antagonistic effect and potential mechanism of specific AKT activator SC79 […]

Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose

Authors: Li Hongsong,  Li Rong,  Wang Lijun,  Liao Dingying,  Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract                              [View PDF]  [Read Full Text] Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin […]