Category: 2022, No. 05

Development and challenge of human lentoid bodies generation

Authors: Fu Qiuli,  Yao Ke DOI: 10.3760/cma.j.cn115989-20220114-00015 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 385-388. Abstract Organoid is one of the hottest areas of research in the field of stem cells, which is an organ in a dish with three-dimensional structure and physiological functions that are highly similar to organs in vivo.At present, […]

Evolution of cataract surgical techniques and improvement of surgical precision

Authors: Xu Wen,  Xu Zhe DOI: 10.3760/cma.j.cn115989-20210715-00413 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 389-394. Abstract With the increase of aging population, the rising demand for cataract surgery, along with the growing demand for post-operative visual quality, the concept of refractive cataract surgery has been put forward, which places more emphasis on the […]

Inhibition of lens epithelial cell migration using different square-edge intraocular lenses in an in vitro capsular bag model

Authors: Lian Feiyue,  Li Yang,  Jiang Lingfeng,  Shen Haoyue,  Zhao Jiangyue,  Yan Xiaoxiao,  Yu Jiaming,  Qin Yu DOI: 10.3760/cma.j.cn115989-20200514-00346 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 395-402. Abstract Objective To establish an in vitro capsular bag model and compare the inhibitory effects of different 360° square-edge intraocular lens (IOL) on lens epithelial cells […]

Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1

Authors: Niu Yantao,  Zhang Li,  Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) and its mechanism regulating silent information regulator factor related enzymes 1 (SIRT1). Methods The HLE-B3 […]

Inhibitory effect of melatonin on pyroptosis of lens epithelium cells and its mechanism

Authors: Yang Xin,  Liu Xuhui,  Meng Jia,  Fang Mengyuan,  Zhang Fengyan DOI: 10.3760/cma.j.cn115989-20210516-00307 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 414-421. Abstract Objective To investigate the inhibitory effect of melatonin on pyroptosis of lens epithelium cells (HLECs) induced by hydrogen peroxide (H2O2) and its mechanism. Methods The cultured HLECs were divided into normal […]

Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism

·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract                  […]

Comparison of postoperative visual quality between toric and non-toric multifocal intraocular lens implantation

Authors: Jiang Yuanfeng,  Tian Fang,  Bu Shaochong,  Zhang Hong DOI: 10.3760/cma.j.cn115989-20200624-00449 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 431-439. Abstract Objective To evaluate and compare the postoperative visual quality after phacoemulsification combined with toric (ART) and non-toric (ReSTOR) multifocal intraocular lens (IOL) implantation. Methods A cohort study was conducted.Thirty-nine cataract patients (50 eyes) […]

Repeatability of CASIA2 for measuring the tilt and decentration of crystalline lens and intraocular lens under non-mydriatic and mydriatic conditions

·Clinical Research· Repeatability of CASIA2 for measuring the tilt and decentration of crystalline lens and intraocular lens under non-mydriatic and mydriatic conditions Tang Yuling, Liao Xuan, Tan Qingqing, Qian Jiulin, Yang Li, Zhou Guimei, Lan Changjun Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Medical School of Ophthalmology & Optometry, North Sichuan Medical […]

Safety and effectiveness of corneal bandage lens for the prevention and treatment of dry eye after cataract surgery in patients with mild meibomian gland dysfunction

Authors: Pan Yanli,  Liang Yan,  Li Yuanbin DOI: 10.3760/cma.j.cn115989-20211216-00696 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 448-453. Abstract Objective To evaluate the efficacy and safety of corneal bandage lens in the treatment of dry eye after cataract surgery in patients with mild meibomian gland dysfunction (MGD). Methods A non-randomized controlled clinical study was […]

Comparison of one-year postoperative visual quality between trifocal and monofocal intraocular lens implantation

Authors: Qin Qin,  Liu Jun,  Chen Hui,  Li Yizhuang,  Bao Lianyun,  He Zifang,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20200211-00060 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 454-460. Abstract Objective To compare the one-year postoperative visual quality after trifocal intraocular lens (IOL) implantation and monofocal IOL implantation. Methods A cohort study was conducted.Forty-one eyes from 41 […]