Tag: Posterior capsular opacification

Inhibitory effect and biological mechanism of Dickkopf-1 on the proliferation of human lens epithelial cells

Authors: Zhang Limin,  Bao Xiuli DOI: 10.3760/cma.j.cn.115985-20190328-00151 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 285-290. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effects of Dickkopf-1(DKK1) on the proliferation of human lens epithelial cells (LECs) and its possible mechanism in order to […]

In vitro epithelial-mesenchymal transition model for LECs of human posterior capsule opacification

Authors: Yang Baoxia,  Wang Ye,  Zhao Xiaowen,  Liu Ting,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.03.004 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 210-217. Abstract                               [Download PDF] [Read Full Text] Background Epithelial-mesenchymal transition (EMT) is one of the pathogenesis mechanisms of posterior capule opcification (PCO). Studying EMT is of important significance […]

Wnt3a-induced extracellular matrix production and gel contraction in human lens epithelial cells

Authors: Bao Xiuli,  Liu Tingting,  Wang Yanyan,  Li Lin DOI: 10.3760/cma.j.issn.2095-0160.2016.07.005 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 597-601. Abstract                               [Download PDF] [Read Full Text] Background Excessive production, deposition and contraction of extracellular matrix (ECM) of human lens endothelial cells (LECs) is one of […]