Category: 2020, No. 04

Standardized application of minimally invasive pars plana vitrectomy for complicated cataract

Authors: Chen Weirong,  Wang Qiwei DOI: 10.3760/cma.j.cn115985.20200325-00199 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 281-284. Abstract Phacoemulsification, an effective surgical method in the treatment of cataracts, is widely used in clinics.Traditional cataract surgery is difficult, risky and has a poor prognosis for special intractable cataract patients.Minimally invasive pars plana vitrectomy (PPV) is the a […]

Inhibitory effect and biological mechanism of Dickkopf-1 on the proliferation of human lens epithelial cells

Authors: Zhang Limin,  Bao Xiuli DOI: 10.3760/cma.j.cn.115985-20190328-00151 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 285-290. Abstract Objective To investigate the effects of Dickkopf-1(DKK1) on the proliferation of human lens epithelial cells (LECs) and its possible mechanism in order to search a new target for the treatment of posterior capsular opacification (PCO). Methods Human LECs […]

Changes in DNA methylation of retinal gene promoter regions and their significance in type 1 diabetic rats

Authors: Li Yahong,  Geng Chao,  Liu Shengnan,  Wang Qi,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.cn115985-20190616-00262 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 291-299. Abstract Objective To study the methylation level of retinal gene promoter region in a rat model of type 1 diabetes (T1D) and investigate the correlation between DNA methylation level and retinal […]

Effects of femtosecond laser mushroom-like penetrating ring-cut on ring incision and corneal endothelial cells

Authors: Jia Guizhen,  Shi Yunqing,  Cheng Mengya,  Cao Xueqian,  Wang Linnong DOI: 10.3760/cma.j.cn115985-20200325-00200 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 300-304. Abstract Objective To evaluate the effect of mushroom-like pattern femtosecond laser enabled penetrating keratoplasty with different laser energies on the ring incision and corneal endothelial cells, and compare with conventional penetrating keratoplasty. Methods According to the point/line separation […]

Development of a remote dedicated doctor platform of ophthalmology and its application efficiency during epidemic of COVID-19

Authors: Gao Zheng,  Wang Xiaoxing,  Huang Xiaoming,  Zhang Jian,  Qu Jia DOI: 10.3760/cma.j.cn115989-20200306-00149 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 305-310. Abstract Objective Due to the circumstances where people being required to home quarantine and eye hospitals being unable to receive patient normally, The application of internet plus technology is explored to build Remote […]

Clinical and genetic characteristics of patients with KCNV2-associated cone dystrophy

Authors: Zhu Tian,  Li Hui,  Wang Lei,  Wei Xing,  Wu Shijing,  Sun Zixi,  Sui Ruifang DOI: 10.3760/cma.j.cn115985-20200117-00030 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 312-318. Abstract Objective To access the genetic defects and clinical characteristics of patients with KCNV2-associated cone dystrophy. Methods Three pedigrees with KCNV2-associated cone dystrophy were recruited in Peking Union Medical College Hospital […]

A phenotype-genotype study of X-linked retinoschisis in RS1 mutations

Authors: Cai Bo,  Liu Yang,  Piao Shunyu,  Wang Shaolin,  Li Wenjing,  Chen Lin,  Tian Tian,  Xue Yajun,  Zhuang Wenjuan DOI: 10.3760/cma.j.cn115985-20190711-00307 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 322-330. Abstract Objective To describe the characteristics of genotype and phenotype in 3 families with X-linked retinoschisis (XLRS) due to RS1 mutations. Methods A cross-sectional approach was adopted.Three XLRS families at the Ningxia Eye Hospital from October […]

Feasibility and clinical significance of intraoperative real-time fundus examination in cataractous eyes

Authors: Su Shu,  Wu Si,  Wu Jian,  Guan Yu,  Wang Yong,  Yang Mei,  Ji Min,  Guan Huaijin DOI: 10.3760/cma.j.cn115985.20190928.00422 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 331-335. Abstract Objective To investigate the feasibility of real-time screening and diagnosing fundus diseases with Wild Field Imaging System (WFIS SW-8000) in the eyes with dense cataract patients. […]

Analysis of the corneal spherical aberration of age-related cataractous eyes

Authors: Liu Wenjie,  Liu Jiewei,  Wang Qi,  Wang Jingjing,  Jia Zhijie,  Wang Bing,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200325-00201 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 336-341. Abstract Objective To investigate the distribution of the spherical aberration in age-related cataractous eyes using the Pentacam HR. Methods A cross-sectional study was performed in Shanxi Eye Hospital from December 2014 to December 2015.The preoperative corneal […]

Application of Chinese VF-11R questionnaire in presenting low vision cataract patients undergoing surgery

Authors: Chen Haisi,  Huang Jinhai,  Gao Rongrong,  Ye Junming,  Chen Min,  Wang Qinmei DOI: 10.3760/cma.j.cn115985-20190930-00426 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 342-347. Abstract Objective To assess the applying value of Chinese shorter version of the Visual Function Index questionnaire (VF-11R-CN) for presenting low-vision cataract pre-operation and post-operation by using minimal clinically important difference […]