Tag: Proteomics

Proteomics analysis of mouse lens supernatant treated with hydrogen peroxide in vitro

Authors: Li Guo,  Chen Ying,  Yan Hong,  Zhou Xiyuan DOI: 10.3760/cma.j.cn115989-20200730-00546 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 382-387. Abstract                              [View PDF] [Read Full Text] Objective To study the protein leakage of mouse lens treated with hydrogen peroxide in vitro, and to identify […]

Application of proteomics in age-related macular degeneration

Authors: Yang Fan,  Sun Xiaodong DOI: 10.3760/cma.j.cn115989-2019-0105-00006 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 72-77. Abstract                               [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is the mainirreversible blinding eye disease in the elderly.Its main pathogenic factors include age, genetic variation and lifestyle, […]

Differential expression and bioinformation analysis of retinal proteins in mice with experimental autoimmune uveitis

Authors: Chen Shuang,  Shao Xianfeng,  Zhang Zhihui,  Chen Nu,  Wu Lingzi,  Cui Xuexue,  Li Xiaorong,  Zhang Xiaomin DOI: 10.3760/cma.j.issn.2095-0160.2019.12.003 Published 2019-12-10 Cite as Chin J Exp Ophthalmol, 2019,37(12): 949-955. Abstract                              [View PDF] [Read Full Text] Objective To observe the expression of retinal […]

Study on iTRAQ-based differential expression protein analysis in nuclear cataract lens with different axial length

Authors: Zhou Haiyan,  Yan Hong,  Yan Weijia,  Wang Xinchuan DOI: 10.3760/cma.j.issn.2095-0160.2019.12.004 Published 2019-12-10 Cite as Chin J Exp Ophthalmol, 2019,37(12): 956-961. Abstract                              [View PDF] [Read Full Text] Objective To identify and verify differentially expressed proteins in lens of nuclear cataract eyes with different axial lengths. Methods […]

Paying attention to proteomics of human tear: clinical significance and application in ocular surface diseases

Authors: Zhou Lei,  Liu Danning DOI: 10.3760/cma.j.issn.2095-0160.2016.02.001 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 97-102. Abstract                               [Download PDF] [Read Full Text] Previous research demonstrated that human tear is a valuable source for biomarker discovery for many ocular surface diseases. Here, we systematically summarized the changes […]

Proteomic research of human retinal microvascular pericytes stimulated with high glucose

Authors:Xiao Mengran,  Zhang Xiaomin,  Shao Xianfeng,  Xiao Jing,  Yang Fuhua,  Zhang Hui,  Ea Vicki L,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2019.09.004 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 707-712. Abstract                               [View PDF] [Read Full Text] Objective To determine the changes of protein expressions in human retinal […]

Advances in vitreous proteomics of vitreoretinal diseases

Authors:Song Minlu,  Wang Fenghua DOI: 10.3760/cma.j.issn.2095-0160.2019.09.016 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 764-768. Abstract                               [View PDF] [Read Full Text] Vitreous is a gelatinous, transparent, highly hydrated matrix that fills the posterior segment of eye.A diversity of proteins that can influence retinal physiology are […]