Category: 2017, No. 02

Role of cysteine-rich protein 61 in ocular neovascular disease

Authors: Guo Jiaxian,  Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2017.02.020 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 189-192. Abstract Cysteine-rich protein 61 (CYR61) is a secreted protein.It consists of four different structural domains and plays an important role in all kinds of cell life activities, such as proliferation, migration, adhesion, angiogenesis, inflammation regulation, embryogenesis and cartilage formation, by […]

Aspirin and the formation of eye neovascularization

Authors: Jiang Mengnan,  Shen Yin,  Xing Yiqiao DOI: 10.3760/cma.j.issn.2095-0160.2017.02.019 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 184-188. Abstract Aspirin is one of the most important non-steroidal anti-inflammatory drugs, could inhibit cyclooxygenase.It has the antipyretic-analgesic, anti-inflammatory and anti-platelet effects, and has been widely used in preventing heart cerebrovascular disease and rheumatic autoimmune disease.Neovascularization is a self-healing mechanism.However, […]

Relationship between autophagy and retinal ganglion cells in animal models of glaucoma

Authors: Fu Shiya,  Zhang Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.02.018 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 180-183. Abstract The main pathological feature of glaucoma is progressive loss of retinal ganglion cells (RGCs), and the damage mechanisms have not been elucidated.Autophagy is a lysosomal degradative process that eliminates damaged cellular constituents, including organelles and long-life proteins.And autophagy plays […]

Research progress in pathogenesis of herpes simplex keratitis

Authors: Cao Nanjue,  Xia Likun DOI: 10.3760/cma.j.issn.2095-0160.2017.02.017 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 175-179. Abstract Herpes simplex keratitis (HSK) is a global high incidence of serious infectious cause of blindness.Chronic visual impairment and visual loss are caused by recurrence of infection, corneal scaring, keratoleukoma, corneal vascularization, lymphangion and so on.According to the current study, […]

Advances in the construction of tissue-engineered cornea in vitro

Authors: Zhang Canwei,  Wu Xinyi DOI: 10.3760/cma.j.issn.2095-0160.2017.02.016 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 170-174. Abstract Corneal transplantation is the most effective treatment for corneal blindness at present, but the shortage of cornea donation and graft rejection are the serious obstacles for its broad application.Construction of tissue-engineered corneal substitutes with good biocompatibility and normal biological […]

Clinical observation of corneal stroma injection of different concentrations of fluconazole for fungal keratitis

Authors: Bai Liguang,  Xin Xin DOI: 10.3760/cma.j.issn.2095-0160.2017.02.015 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 165-169. Abstract Background Fungal keratitis can cause serious damage to visual function of corneal infective disease, which is more difficult to treat.In recent years, injecting antifungal drugs to the corneal stroma not only enrich the treatment of the disease, but also […]

Spectrum of fungal keratitis change in South China

Authors: Gong Hua,  Tan Yiwei,  Gong Xiangming,  Liang Jiahui,  Cai Zhiwei  DOI: 10.3760/cma.j.issn.2095-0160.2017.02.014 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 161-164. Abstract Background Fungal keratitis has a high incidence in China and its clinical treatment is very difficult, and its etiology diagnosis and appraisal is the premise to improve the prognosis of disease.With the changes of regional environment […]

Analysis of causative genus of keratomycosis and antifungal susceptibility in tropical area of China

Authors: Chen Xiaolian,  Liu Hongshan,  He Hong,  Wu Jiaochan,  Hu Xianlyu,  Zhong Xingwu DOI: 10.3760/cma.j.issn.2095-0160.2017.02.013 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 156-160. Abstract Background Hainan Island is a tropical and subtropical area in China, with a suitable climate for fungal growth and breeding.Keratomycosis occurred frequently in this area.It is essential to analyze the causative genus and investigate the […]

Dynamic observation of corneal reinnervation after small incision lenticule extraction at cap by confocal microscope

Authors: Ge Qingman,  Cui Chuanbo,  Kong Deyan,  Song Li DOI: 10.3760/cma.j.issn.2095-0160.2017.02.012 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 151-155. Abstract Background Corneal reinnervation of subbasal nerve plexus have been found after small incision lenticule extraction(SMILE). However, there were few reports about corneal reinnervation mode and dynamic changes at the corneal cap in different time points postoperation. Objective […]

Association between corneal volume change and corneal biomechanical property before and after small incision lenticule extraction in myopia

Authors: Wei Pinghui,  Wang Yan,  Li Hua,  Dou Rui,  Zhang Jiamei,  Zhao Wei,  Li Liuyang DOI: 10.3760/cma.j.issn.2095-0160.2017.02.011 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 146-150. Abstract Background The relationship between corneal central thickness (CCT) and corneal biomechanical property does not reflect the effective amount of ablated tissue because CCT measures only the change in a single point.Corneal volume (CV) is […]