Authors: Qin Minggao, Zhang Qiuli DOI: 10.3760/cma.j.cn115989-20241029-00301 Published: 2026 -03 -10 Citation Qin Minggao, Zhang Qiuli. Research progress on retinal ganglion cell damage induced by glaucoma and programmed cell death pathways[J]. Chin J Exp Ophthalmol, 2026, 44(3):301-306. DOI: 10.3760/cma.j.cn115989-20241029-00301. ABSTRACT [Download PDF] [Read Full Text] Glaucoma, the second leading cause of global […]
Tag: Autophagy
Negative regulation of autophagy in retinal ganglion cells by Opn5 through inhibiting Egr-1 nuclear translocation
Authors: Tong Liyang, He Danxue, Fu Chenxi, Zhang Lingmin, Hua Chaoqun DOI: 10.3760/cma.j.cn115989-20250514-00152 Published: 2026 -01 -10 Citation Tong Liyang, He Danxue, Fu Chenxi, et al. Negative regulation of autophagy in retinal ganglion cells by Opn5 through inhibiting Egr-1 nuclear translocation[J]. Chin J Exp Opthalmol, 2026, 44(1):19-26. DOI: 10.3760/cma.j.cn115989-20250514-00152. ABSTRACT [Download PDF] [Read Full […]
Inhibitory effect of exosome-loaded KV11 on corneal neovascularization via VDAC1 and autophagy
Authors: Chen Wenqian, Du Wei, Yu Wenzhen DOI: 10.3760/cma.j.cn115989-20220402-00132 Published 2024-02-10 Cite as Chin J Exp Ophthalmol, 2024, 42(2): 108-116. Abstract 【Read Full Text】【Download PDF】 Objective To investigate the effects and mechanism of exosome (EXO)-loaded kringle V11 (KV11) delivery on corneal neovascularization (CNV). Methods […]
Research progress in autophagy on dry age-related macular degeneration
Authors: Yan Quan, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2015.10.018 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 949-952. Abstract [Download PDF] [Read Full Text] Age-related macular degeneration (AMD) is a common cause of vision loss and living quality impairment in elderly people.Dry AMD […]
Inhibitory effect of microRNA-23b-3p on high glucose-induced autophagy and apoptosis of human lens epithelial cells and its mechanism
·Experimental Research· Role and mechanism of microRNA-23b-3p in regulating high glucose-induced autophagy and apoptosis of human lens epithelial cells Liu Wenlan, Wang Li, Yang Yang, Yan Jin School of Medical Technology, Xi’an Medical University, Xi’an 710021, China Corresponding author: Wang Li, Email: 63148645@qq.com [Abstract] […]
Role of hydrogen sulfide in the pathogenesis of diabetic retinopathy
Authors: Chen Fei, Zhang Xuedong DOI: 10.3760/cma.j.cn115989-20210914-00512 Published 2021-12-10 Cite asChin J Exp Ophthalmol, 2021, 39(12): 1124-1128. Abstract [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a common and important ocular complication of diabetes and has become one of the leading blindness diseases in […]
Research progress of autophagy in the pathogenesis of glaucoma
Authors: Xu Yaohan, Han Wei DOI: 10.3760/cma.j.cn115989-20210712-00407 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 923-928. Abstract [View PDF] [Read Full Text] Glaucoma, a neurodegenerative disease characterized by progressive death of retinal ganglion cells (RGCs) and chronic axonal degeneration, is often associated with elevated […]
Regulatory effect of edaravone on the photoreceptor autophagy at the early stage of experimental retinal detachment in rats
Authors: Kang Ziwei, Ren Xiuyu, Zhang Yanchun, Pei Cheng, Zhang Nana, Xia Yimin, Yang Jingru DOI: 10.3760/cma.j.cn115989-20200228-00123 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 776-784. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of edaravone, a free radical scavenger, on […]
Role of autophagy in the occurrence and development of glaucoma
Authors: Tian Jingjing, Jia Zhiyang, Fan Fang DOI: 10.3760/cma.j.cn115989-20200326-00213 Published 2020-05-10 Cite as Chin J Exp Ophthalmol, 2020,38(05): 442-446. Abstract [View PDF] [Read Full Text] Glaucoma is a chronic neurodegenerative disease of the optic nerve accompanied by apoptosis of the retinal ganglion cells, atrophy and depression […]
Research progress of FYCO1 gene mutation
Authors:He Chenhao, Li Yuying, Zhong Zilin, Chen Jianjun DOI: 10.3760/cma.j.issn.2095-0160.2019.09.014 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 755-758. Abstract [View PDF] [Read Full Text] FYVE and coiled-coil domain containing 1(FYCO1) is an adaptor of cellular autophagy which has RUN domain, […]