Authors: Deng Zhenhua, Ye Zimeng, Gong Bo, Lu Fang DOI: 10.3760/cma.j.issn.2095-0160.2017.08.010 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 716-720. Abstract [Download PDF] [Read Full Text] Background High myopia is one of the primary factors of visual impairment, and its prevention and management are […]
Category: 2017, No. 08
Mutation analysis of a Chinese pedigree of Leber hereditary optic neuropathy with only male patients
Authors: Lu Xiaoyan, Jin Xuemin, Shi Xiaoling DOI: 10.3760/cma.j.issn.2095-0160.2017.08.009 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 710-715. Abstract [Download PDF] [Read Full Text] Background Leber hereditary optic neuropathy (LHON) is a maternally inherited disorder characterized by a bilateral acute or subacute painless […]
Pedigree and clinical characteristics in a Chinese family with lattice corneal dystrophy
Authors: Peng Shiming, Zhao Jun, Zhu Tianhui, Huang Xiaosheng, Chen Wenjie, Mei Shaoyi, Wang Yan DOI: 10.3760/cma.j.issn.2095-0160.2017.08.007 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 704-708. Abstract [Download PDF] [Read Full Text] Background Lattice corneal dystrophy (LCD) is a progressive disease, whose clinical features are varied in different stages.It is rarely be […]
Inhibitory effects of microRNA-375 on biological behaviour of human retinal capillary endothelial cells induced by hypoxia
Authors: Zhu Jiang, Ren Mei, Xu Zhiguo DOI: 10.3760/cma.j.issn.2095-0160.2017.08.005 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 695-702. Abstract [Download PDF] [Read Full Text] Background Studies showed that microRNA (miR)-375 suppresses the growth, apoptosis, migration and adhesion of tumor cells, and it plays a regulation to the […]
Aggravation effects of JAK-STAT signaling pathway in retinal ischemia reperfusion injury
Authors: Yang Le, Shi Rui, Shen Jiaquan, Xue Yushun DOI: 10.3760/cma.j.issn.2095-0160.2017.08.004 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 690-694. Abstract [Download PDF] [Read Full Text] Background Retinal ischemia reperfusion injury (RIRI) is a common pathological process of many retinal vascular diseases with comprehensive pathogenesis mechanism.Researches showed that […]
Construction of combined lentiviral vectors for rat Slit2 gene RNA interfering and its down-regulation effects on Slit2 gene in rat retinal pigment epithelial cells
Authors: Jiang Shaoqiu, Zhou Xiyuan DOI: 10.3760/cma.j.issn.2095-0160.2017.08.003 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 683-689. Abstract [Download PDF] [Read Full Text] Background Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years old, of which 90% cases are caused by […]
Inhibition of adenovirus-mediated recombinant Tum5 gene overexpression on human umbilical vein endothelial cells in physiological status
Authors: Jia Yurong, Yang Wei, Zhang Hong, Zhang Yan, Sun Jing DOI: 10.3760/cma.j.issn.2095-0160.2017.08.002 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 677-682. Abstract [Download PDF] [Read Full Text] Background Tumstatin is the most active endogenous angiogenesis inhibitor, which has a marked inhibitory effect on pathological neovascularization, and Tum5 is […]
Clinical phenotype assessment is very important in mutation analysis for patients with hereditary eye disease
Author: Li Yang DOI: 10.3760/cma.j.issn.2095-0160.2017.08.001 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 673-676. Abstract [Download PDF] [Read Full Text] Sanger sequencing technology is the most commonly used method for genetic analysis in inherited eye disease in the past few decades […]