Category: Experimental Science

The Th1/Th2-associated cytokines in the animal model of Graves ophthalmopathy

Authors:Yang Yuli,  Luo Qingli,  Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.11.003 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 971-977. Abstract                              [Download PDF] [Read Full Text] Background Graves opthalmopathy (GO) is an autoimmune disease, and its pathogenesis is not clear.Recent reports found that the imbalance of Th1/Th2 type immune response may be […]

The effects of fluoxetine and its machanism on the restores of visual cortex plasticity in the adult rats by visual electrophysiological research

Authours:Xie Laiqing,  Xu Guoxu,  Ni Yong,  Wei Xiaohong,  Lou Hui DOI: 10.3760/cma.j.issn.2095-0160.2016.11.002 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 965-970. Abstract                              [Download PDF] [Read Full Text] Background Fluoxetine (Flx), a selective serotonin reuptake inhibitor, promotes neurogenesis and synaptogenesis in the adult hippocampus.So it is inferred that Flx plays a role […]

Model making of radioactive optic nerve injury

Authors:Cheng Xianhua,  Gu Xuejun,  Li Zhiying,  Ji Jianping DOI: 10.3760/cma.j.issn.2095-0160.2016.12.009 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1092-1096. Abstract                              [Download PDF] [Read Full Text] Background Radiation-induced optic neuropathy (RION) is a severe complication after radiotherapy for head and neck cancer, which threatens the visual acuity and quality of life […]

Iinhibitory effects of miR-200a on proliferation and migrating ability of conjunctival fibroblasts and its mechanism

Authors:Yin Xue,  Liang Ya,  Yuan Zhilan DOI: 10.3760/cma.j.issn.2095-0160.2016.12.008 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1087-1091. Abstract                              [Download PDF] [Read Full Text] Background Scarring of surgical area, the most important factor, leads to the failure of glaucoma filtering surgeries.Therefore, more and more attentions are paid to the causes […]

Inhibitory effects of α-crystallin on optic nerve astrocytes proliferation, activation and secretion stimulated by lipopolysaccharide

Authors:Liu Xiao,  Shao Weiyang,  Gu Xianliang,  Wang Yi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.007 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1082-1086. Abstract                              [Download PDF] [Read Full Text] Background Glial scaring induced by the activation and proliferation of astrocytes after optical nerve damage is one of causes of neural axons difficult to regeneration.Researches […]

Application of modified retinal flatmount combined with immunofluorescence staining in oxygen-induced retinopathy model

Authors:Li Rong,  Yao Guomin,  Wang Xiaodi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.005 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1077-1080. Abstract                              [Download PDF] [Read Full Text] Background Retinal flatmount of oxygen-induced retinopathy (OIR) animal models is a useful tool in the study of ischemic retinopathy.The retinas of OIR of rat or mouse […]

α-Melanocyte-stimulating hormone inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy

Authors:Yang Qianhui,  Zhang Yan,  Bo Qiyu,  Cao Yunshan,  Yang Wei,  Wang Fei,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2016.12.004 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1072-1076. Abstract                               [Download PDF] [Read Full Text] Background Retinal neovascularization (RNV) occurs in multiple eye diseases, which can lead to bleeding and retinal detachment.Therefore, inhibition of pathological RNV is […]

Inhibitory effects of jiajianzhujing decoction containing serum on proliferation of rat choroidal vascular endothelial cells

Authors:Liu Yanjiang,  Kang Zefeng,  Xing Kai,  Liu Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.12.003 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1065-1071. Abstract                              [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) of macular zone is one of blinding eye diseases.Conventional treatment methods include photodynamic therapy and intravitreal injection of anti-vascular endothelial growth […]

Development of cooperative robot-assistant surgery system for vitreoretinal microsurgery and its feasibility test in an animal model

Authors: Chen Yiqi,  Zhang Chaote,  Hong Mingsheng,  Su Lingya,  Tao Jiwei,  Yang Yang,  Xiao Jingjing,  Shen Lijun DOI: 10.3760/cma.j.issn.2095-0160.2017.01.008 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 38-41. Abstract                               [Download PDF] [Read Full Text] Background Robotic systems are increasingly utilized in numerous disciplines including ophthalmology.Several reports showed potential benefits of robotic-assisted surgery, […]

Protection of sericin to retinal microvessels and its mechanism in diabetic rats

Authors: Yu Hongfei,  Dong Zhijun,  Zhang Tiemin,  Yang Fan DOI: 10.3760/cma.j.issn.2095-0160.2017.01.007 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 32-37. Abstract                              [Download PDF] [Read Full Text] Background Diabetic retinopathy (DR) is a chronic inflammatory disease, with pathological changes of retinal microvessels.Studies demonstrated that sericin has anti-inflammation and anti-oxidation […]