Tag: Rabbits

Comparison of the pharmacokinetics of gatifloxacin ophthalmic gel in rabbit ocular tissues with different dosing frequencies

Authors: Wang Xiaotong,  Zhao Xin,  Zu Wei,  Shen Xu,  Chen Shichao,  Yang Qiang DOI: 10.3760/cma.j.cn115989-20220513-00215 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 621-628. Abstract                            【Download PDF】【Read Full Text】 Objective To establish a method for determining the concentration of gatifloxacin in […]

Feasibility of adipose tissue-derived stem cell sheet fabricated ex vivo on temperature-responsive scaffolds as seed cells for ocular surface reconstruction

Authors: Wei Qiaoling,  Xu Jianjiang DOI: 10.3760/cma.j.issn.2095-0160.2015.09.003 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 781-786. Abstract                            [Download PDF] [Read Full Text] Background Development of corneal tissue engineering creates a new therapeutic method for severe corneal diseases. However, ideal seed cells and […]

Expressions of cyclin dependent kinase inhibitors p21 and p27 in rabbit retina and their association with proliferation

Authors: Wang Xiaohui,  Xie Maosong,  Chen Limin,  Xu Guoxing DOI: 10.3760/cma.j.issn.2095-0160.2015.11.003 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 969-973. Abstract                              [Download PDF] [Read Full Text] Background The imbalance of cell cycle regulation results in proliferative vitreoretinopathy (PVR). Studing the effects […]

Toxic effects of manganese ion eyedrops to ocular anterior segment

Authors: Lei Miao,  Zhu Yu,  Liang Shenzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.06.008 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 510-515. Abstract                              [Download PDF] [Read Full Text] Background A preliminary study determined an application of manganese ion eyedrops in tracing observation of visual system […]

Ocular pharmacokinetics of topical administration of butenafine nanomicelles in rabbit eyes

Authors: Lu Ping,  Liang Zhen,  Zhang Zhen,  Yang Jingjing,  Song Fei,  Li Jingguo,  Zhou Tianyang,  Zhang Junjie DOI: 10.3760/cma.j.cn115989-20200526-00374 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1038-1044. Abstract                               [View PDF] [Read Full Text] Objective To study the pharmacokinetics of the broad-spectrum antifungal drug […]

Protective effects of thymosin β4 on ethanol-induced rabbit corneal epithelial cell damage in vitro

Authors: Jiang Zhixin,  Hao Peng,  Tang Xin,  Li Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.003 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 108-114. Abstract                              [Download PDF] [Read Full Text] Background Laser assisted subepithelial keratomileusis (LASEK) is one of surgical procedures for refractive correction. Dilute alcohol that is used for the removal […]

Feasibility of bacterial cellulose membrane as biological scaffold for construction of tissue engineering corneal epithelium

Authors: Cao Jingjie,  Zhang Chen,  Zhao Shaozhen,  Wan Yizao,  Hu Da DOI: 10.3760/cma.j.issn.2095-0160.2016.02.006 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 121-124. Abstract                              [Download PDF] [Read Full Text] Background Corneal transplantation is a primary method for the treatment of serious corneal diseases, but its application […]

Pathogenesis and treatment of overwhelming inflammation induced by Pseudomonas aeruginosa keratitis in rabbit

Authors: Liang Qingfeng,  Li Bin,  Zhang Yang,  Labbe Antoine DOI: 10.3760/cma.j.issn.2095-0160.2016.02.007 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 125-131. Abstract                            [Download PDF] [Read Full Text] Background Infectious keratitis is common blinding eye disease in China. Inflammatory runaway reaction often occurs in infectious keratitis, and its mechanism and treating […]

Suppressing effect of p21WAF1/CIP1 on traumatic proliferative vitreoretinopathy in rabbits

Authors: Yuan Zhigang,  You Caiyun,  Han Jindong,  Li Haiyan,  Yan Hua DOI: 10.3760/cma.j.issn.2095-0160.2016.05.008 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 420-425. Abstract                              [Download PDF] [Read Full Text] Background p21 is a cyclin-dependent kinase inhibitor, and it can prevent cells from going through the G1/S […]

Inhibition of curcumin on the expression of IL-1β-induced nuclear factor-κB-dependent inflammatory gene in rabbit RPE cells

Authors: Liu Liya,  Ma Jingxue,  Liu Danyan,  An Jianbin,  Zhou Nalei,  Ma Yuelei DOI: 10.3760/cma.j.issn.2095-0160.2016.09.008 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 804-812. Abstract                              [Download PDF] [Read Full Text] Background Interleukin-1β (IL-1β) is an important inflammation-related factor in the initial stage of proliferative vitreoretinopathy (PVR). The previous research showed […]