Authors: Wang Shujing, Shao Zhengbo DOI: 10.3760/cma.j.cn115989-20200302-00131 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 881-884. Abstract [View PDF] [Read Full Text] Glaucoma is a disorder that leads to retinal ganglion cells (RGCs) apoptosis, visual field loss and optic nerve degeneration.The RGCs death is […]
Category: Review
Progress in research of Müller cell reprogramming in retinal regeneration
Authors: Zhao Zhenzhen, Liang Jian DOI: 10.3760/cma.j.cn115989-20200110-00019 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 885-889. Abstract [View PDF] [Read Full Text] Müller glia, the major type of glial cells in retina, is crucial for maintaining retinal homeostasis.Although Müller cells have the features to […]
Modification of mesenchymal stem cell derived exosomes and its application prospects in the treatment of eye disease
Authors: Lin Hao, Wang Ying DOI: 10.3760/cma.j.cn115989-20200319-00186 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 890-894. Abstract [View PDF] [Read Full Text] Mesenchymal stem cells (MSCs) were extensively explored as new therapeutic agents in cell-based therapy due to their immunomodulatory and pro-angiogenic characteristics.Exosomes are […]
Advances in corneal basement membrane modulating stromal fibrosis
Authors: Wu Jinling, Li Xia DOI: 10.3760/cma.j.cn115989-20200519-00355 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 895-899. Abstract [View PDF] [Read Full Text] Basement membranes are highly specialized forms of extracellular matrix and their formation is a prerequisite for normal tissue […]
Progress in matrix metalloproteinase 2 and 9 regulating corneal neovascularization
Authors: Zhang Jiahao, Zhang Yan, He Yuxi DOI: 10.3760/cma.j.cn115989-20190226-00085 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 900-904. Abstract [View PDF] [Read Full Text] Corneal neovascularization (CNV) is a pathological process of angiogenesis that can cause severe corneal damage.CNV has been widely demonstrated to […]
Research progress of exosomes in diabetic retinopathy
Authors: Zhang Hui, Zhang Xiaomin, Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200424-00285 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 799-803. Abstract [View PDF] [Read Full Text] Exosomes are small extracellular vesicles secreted by cells and carry many biological molecules, such as mRNA, microRNA, proteins, and transcription […]
Application of machine learning in auxiliary diagnosis of corneal related diseases
Authors: Zhang Zijun, Liang Qingfeng DOI: 10.3760/cma.j.cn115989-20200201-00045 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 804-808. Abstract [View PDF] [Read Full Text] Machine learning, as the main technical direction of artificial intelligence, can help ophthalmologists to interpret and analyze the large amount of data […]
Application of single-cell RNA sequencing in visual system
Authors: Liu Yifan, Shen Yin DOI: 10.3760/cma.j.cn115989-20200509-00325 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 704-709. Abstract [View PDF] [Read Full Text] Single-cell RNA sequencing (scRNA-seq) is an emerging technology that observes transcriptomes’ differences between individual cells at the cellular level.The basic strategy is to […]
Review and analysis on knockout mouse models with cataract
Authors: Wu Zehua, Liu Xiangyuan, Li Yuying, Zhong Zilin, Chen Jianjun DOI: 10.3760/cma.j.cn115989-20190227-00087 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 710-714. Abstract [View PDF] [Read Full Text] Cataract is the leading cause of blindness worldwide, which is a generally clinical and genetic heterogeneity eye […]
Advances of genetics of age-related macular degeneration
Authors: Xu Jingjing, Hu Yuntao DOI: 10.3760/cma.j.cn115989-20200509-00324 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 715-720. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is one of the leading causes of blindness for the elderly over 50, characterized by loss of central vision […]