Authors: Wei Xing, Sui Ruifang DOI: 10.3760/cma.j.cn115989-20200627-00457 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 737-742. Abstract [View PDF] [Read Full Text] Inherited retinal degeneration (IRD), a group of diseases often causing irreversible blindness, with multiple pathogenesis, still lacks effective treatments currently.Development of effective […]
Category: Review
Role of circRNA in ophthalmic diseases
Authors: Yang Guang, Zhang Dan, Ma Xiaopeng DOI: 10.3760/cma.j.cn115989-20191011-00437 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 743-748. Abstract [View PDF] [Read Full Text] Circular RNA (circRNA) is a closed loop molecule generated by the back-splicing of pre-mRNA.CircRNA can act as microRNA (miRNA) sponge […]
Related clinical trials and prospects of gene therapy for neovascular age-related macular degeneration
Authors: Zhang Wei, Yan Hua DOI: 10.3760/cma.j.cn115989-20210113-00033 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 749-754. Abstract [View PDF] [Read Full Text] Neovascular macular degeneration (nAMD) is one of the main eye diseases causing blindness in the elderly population.Early detection and early treatment are […]
Characteristics of autosomal dominant retinal diseases and gene therapy strategies
Authors: Liu Yanbo, Pang Jijing DOI: 10.3760/cma.j.cn115989-20210329-00215 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 755-760. Abstract [View PDF] [Read Full Text] Inherited retinal diseases (IRDs), one type of the major eye diseases resulting in blindness, can be caused by more than 270 identified […]
Research progress of intravitreal injections for nonarteritic anterior ischemic optic neuropathy
Authors: He Lu, Chen Changzheng DOI: 10.3760/cma.j.cn115989-20201104-00739 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 641-644. Abstract [View PDF] [Read Full Text] Nonarteritic anterior ischemic optic neuropathy (NAION) is a common type of acute optic neuropathy in elderly, characterized by optic […]
Advances in the treatment of idiopathic macular epiretinal membrane
Authors: Jiao Mingfei, Li Xiaorong DOI: 10.3760/cma.j.cn115989-20201104-00738 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 645-648. Abstract [View PDF] [Read Full Text] Idiopathic epiretinal membrane (iERM) is one of common fibroblast proliferative diseases in vitreoretinal interface and is significantly associated with aging.The treatment and […]
Specialized proresolving lipid mediators and eye diseases
Authors: Zhu Yingting, Li Yiqing, Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20200607-00402 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 649-654. Abstract [View PDF] [Read Full Text] Novel endogenous lipid-mediated molecules including lipoxins, resolvins, protectins, and maresin families are discovered recently and are collectively called specialized proresolving […]
Warburg effect of retinal energetic metabolism and its regulatory mechanism
Authors: Han Guoge, Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200717-00505 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 655-660. Abstract [View PDF] [Read Full Text] Retinal metabolism includes material metabolism and energetic metabolism.Retina is one of the most energy-consuming nerve tissue in human body and mainly relies […]
Progress in pathogenesis and treatment of the elevated intraocular pressure resulted from thyroid associated ophthalmopathy
Authors: Guo Zhenfeng, Zhao Liang, Sun Fengyuan DOI: 10.3760/cma.j.cn115989-20191022-00459 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 661-664. Abstract [View PDF] [Read Full Text] In adult orbital diseases, thyroid associated ophthalmopathy (TAO) is of very high incidence rate, and it can seriously affect patients’ […]
Clinical characteristics of interface fluid syndrome after LASIK: a systematic review
Authors: He Qing, Wang Xiu, Gu Tianpu, Xie Caiyuan, Wei Ruihua DOI: 10.3760/cma.j.cn115989-20210310-00156 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 557-562. Abstract [View PDF] [Read Full Text] Objective To evaluate the clinical features of interface fluid syndrome (IFS) after laser in situ keratomileusis (LASIK). […]