Category: Review

Effects of ubiqutin-proteasome system in retinopathy and their mechanism

Authors: Wang Shuai,  Liu Shengqiang DOI: 10.3760/cma.j.issn.2095-0160.2019.10.015 Published 2019-10-10 Cite as Chin J Exp Ophthalmol, 2019,37(10): 843-848. Abstract                               [View PDF] [Read Full Text] Ubiquitin-proteasome system (UPS) is the important protein degradation system in eukaryotic cells, participates in cell cycle, gene transcription, antigen-presenting, cell proliferation and differentiation, signal […]

Research advancement on necroptosis in retinal cell death

Authors: Lu Bing,  Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2016.01.018 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 85-88. Abstract                            [Download PDF] [Read Full Text] Retinal pigment epithelium cells, retinal ganglial cells and photoreceptor cells play vital roles in maintaining the function of retina and choroid.Retinal cell death is the […]

Relationship between macrophage polarization and age-related macular degeneration

Authors: Liu Fang,  Li Jiaqing,  Ding Xiaoyan DOI: 10.3760/cma.j.issn.2095-0160.2016.01.019 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 89-91. Abstract                            [Download PDF] [Read Full Text] Age-related macular degeneration (AMD) is one of the leading causes to blindness worldwide in elderly population.Innate immune system elements, such as macrophages and cytokines, […]

The role of Toll like receptors in retinal microglia in retinal inflammatory and ischemic diseases

Authors: Xu Wenqin,  Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2016.01.020 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 92-96. Abstract                              [Download PDF] [Read Full Text] Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing pathogen-associated molecular patterns derived from various microbes and self-derived molecules derived […]

Corneal collagen cross-linking: opportunities and challenges

Authors: Dong Zixian,  Zhou Xingtao DOI: 10.3760/cma.j.issn.2095-0160.2016.02.018 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 181-183. Abstract                            [Download PDF] [Read Full Text] Recently, collagen cross-linking has been an effective and high-security method for the treatment of primary and secondary corneal ectasia and other low biomechanical diseases. In […]

Research progress in corneal neovascularization and microenvironment

Authors: Hou Peili,  Lu Yan,  Huang Zhenping DOI: 10.3760/cma.j.issn.2095-0160.2016.02.019 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 184-188. Abstract In a variety of pathological conditions, capillaries grow from corneal limbus to the central cornea area, to form corneal neovascularization (CNV). CNV destroys the normal corneal microenvironment, reduces the transparency of cornea, seriously affects visual acuity and leads […]

Research advances of tear osmolarity

Authors: Wang Wei,  Li Guigang,  Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2016.02.020 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 189-192. Abstract                              [Download PDF] [Read Full Text] Tear osmolarity is an important factor in maintaining tear film stability. With the development of testing technology for tear osmolarity, more researches on […]

Applications of capsular bag model in posterior capsular opacification

Authors: Zhang Chunmei,  Jin Na,  Liu Hongling DOI: 10.3760/cma.j.issn.2095-0160.2016.03.017 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 276-279. Abstract                         [Download PDF] [Read Full Text] Posterior capsular opacification (PCO), also known as after-cataract, is the most frequent complication and the primary cause for visual decrease after extracapsular cataract surgery.At present, […]

Advanced researches on treatment of idiopathic macular holes

Authors: Gan Chunlan,  Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2016.03.018 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 280-283. Abstract                               [Download PDF] [Read Full Text] Idiopathic macular hole (IMH) is characterized by a central retinal defect without any ocular diseases.Internal limiting membrane peeling (ILMP) of the retina is proved […]

Current researches on proteins associated with polypoidal choroidal vasculopathy

Authors: Zhang Yafang,  Li Dai DOI: 10.3760/cma.j.issn.2095-0160.2016.03.019 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 284-288. Abstract                            [Download PDF] [Read Full Text] Polypoidal choroidal vasculopathy (PCV) is one of the ocular fundus diseases and can cause severe visual impairment or blindness.The occurrence of PCV may be related […]