Authors: Zhang Lian, Song Jike, Tang Kai, Zheng Fengming, Guo Junguo, Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2016.08.003 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 684-690. Abstract [Download PDF] [Read Full Text] Background Studies show that regulatory T cells (Treg) are a kind of T cell subsets to […]
Tag: Disease models
The Th1/Th2-associated cytokines in the animal model of Graves ophthalmopathy
Authors：Yang Yuli, Luo Qingli, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.11.003 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 971-977. Abstract [Download PDF] [Read Full Text] Background Graves opthalmopathy (GO) is an autoimmune disease, and its pathogenesis is not clear.Recent reports found that the imbalance of Th1/Th2 type immune response may be […]
Promoting ocular surface restoration effects and anti-inflammatory mechanism of thymosin beta 4 in rat dry eye
Authors: Zhang Huiqin, Li Ying, Feng Lina, Xu Yonggen DOI: 10.3760/cma.j.issn.2095-0160.2017.02.005 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 114-121. Abstract [Download PDF] [Read Full Text] Background Studies showed that inflammation is associated with the pathogenesis and development of dry eyes, and tumor necrosis […]
Experimental study on inhibiting graft rejection following high-risk cornea transplatation by resolvinE1 in mice
Authors: Wang Han, Luo Dan, Li Ting, Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2017.03.005 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 209-215. Abstract [Download PDF] [Read Full Text] Background The conventional drugs for preventing and treating graft rejection have the risks of inducing adverse responses.Researches showed that resolvinE1 (RvE1) can […]
Combinatorial protective effects of α-melanocyte-stimulating hormone and carboxymethylcellulose on ocular surface in dry eye rat models
Authors: Dou Zexia, Ru Yusha, Liu Huijuan, Zeng Xiaoyu, Meng Zhu, Gu Zhongxiu, Zhang Yan, Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2017.06.004 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 498-505. Abstract [Download PDF] [Read Full Text] Background Reasearches showed that α-melanocyte-stimulating hormone (α-MSH) inhibits inflammation and ameliorates the ocular surface abnormalities in a scopolamine-induced […]
Dynamic expression changes of Smad3 and type Ⅰ collagen in sclera of progressive myopia in guinea pigs
Authors: Jiang Bo, Wu Zhangyou, Zhu Zicheng, Hu Wei, Zhan Xin DOI: 10.3760/cma.j.issn.2095-0160.2017.06.003 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 491-497. Abstract [Download PDF] [Read Full Text] Background Sclera remodeling process in axial elongation is one of the main pathological mechanisms of axial myopia progression.Studies confirmed that transforming […]
Inflammatory-promoting roles of thymic stromal lymphopoietin and interleukin-4 in allergic conjunctivitis mice
Authors: Ning Chanhui, Zheng Xiaofen, Li Bing DOI: 10.3760/cma.j.issn.2095-0160.2017.09.009 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 811-815. Abstract [Download PDF] [Read Full Text] Background Researches showed that thymic stromal lymphopoietin (TSLP) is an interleukin-17-like inflammatory factor and plays important roles in the pathogenesis and development of […]
Inflammation-causing effects and mechanism of natural killer cells in experimental autoimmune uveitis rats
Authors: Li Mohan, Bao Ning, Liu Dongwei, Tao Liming, Jiang Zhengxuan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.007 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 799-804. Abstract [Download PDF] [Read Full Text] Background Experimental autoimmune uveitis (EAU) is a common animal model of uveitis.Natural killer (NK) cells have been confirmed to be a […]
Dynamic expression and mechanism of γδ T cells in the spleen of mouse with experimental autoimmune uveitis
Authors: Wang Beibei, Tian Qingmei, Xie Xiaofeng, Song Jike, Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2017.09.006 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 793-798. Abstract [Download PDF] [Read Full Text] Background Previous studies showed that the pathogenesis of uveitis is related to γδ T cells.However, it remains unclear that how these […]
Degeneration of short-wavelength cone cells in rd12 mice
Authors: Li Xia, Zhang Hua, Dai Xufeng, Pang Jijing DOI: 10.3760/cma.j.issn.2095-0160.2017.11.003 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 970-975. Abstract [Download PDF] [Read Full Text] Background Retinitis pigmentosa (RP) is one of the causes of congenital blindness.It is well known that the degeneration process of rod cells […]