Tag: Disease models

Expression changes of brain-derived neurotrophic factor in retina of oxygen-induced retinopathy

Authors: Duan Haixia,  Guo Kai,  Wang Banwei DOI: 10.3760/cma.j.issn.2095-0160.2016.01.011 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 56-59. Abstract                              [Download PDF] [Read Full Text] Background Neovascular diseases such as retinopathy of prematurity often leads to irreversible vision loss.The study on oxidative damage mechanism is becoming more and […]

Dysfunction of tear film and ultrastructural changes of corneal epithelial cells in castrated male mice

Authors: Li Li,  Wang Shuangmei,  Zheng Xuan,  Kang Qianyan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.002 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 103-107. Abstract                            [Download PDF] [Read Full Text] Background Studies indicate that the decline of androgen level affects the secretion function of epithelial cells of meibomian glands and lacrimal glands, which […]

Pathogenesis and treatment of overwhelming inflammation induced by Pseudomonas aeruginosa keratitis in rabbit

Authors: Liang Qingfeng,  Li Bin,  Zhang Yang,  Labbe Antoine DOI: 10.3760/cma.j.issn.2095-0160.2016.02.007 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 125-131. Abstract                            [Download PDF] [Read Full Text] Background Infectious keratitis is common blinding eye disease in China. Inflammatory runaway reaction often occurs in infectious keratitis, and its mechanism and treating […]

A comparative study of two common optic nerve crush models in rats

Authors: An Jing,  Yin Hao,  Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2016.04.004 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 305-311. Abstract                              [Download PDF] [Read Full Text] Background Optic nerve crush (ONC) model is an available tool in the basic research on the mechanism and treatment of optic […]

Thrombolysis of plasmin-ΔK on photochemically induced branch retinal vein occlusion after intravitreal injection in rats

Authors: Chen Wu,  Mo Wei,  Huang Xin,  Ou-yang Yanling,  Song Houyan,  Zhang Zhiyun DOI: 10.3760/cma.j.issn.2095-0160.2016.05.006 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 408-413. Abstract                              [Download PDF] [Read Full Text] Background Retinal vein occlusion is a common retinal vascular diseases.Thromblysis and anticoagulation therapies are main […]

Progress in developing a sodium iodate-induced retinitis pigmentosa animal model

Authors: Fan Meihua,  Chen Yongxiong DOI: 10.3760/cma.j.issn.2095-0160.2016.09.018 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 860-864. Abstract                              [Download PDF] [Read Full Text] Retinitis pigmentosa (RP) is a group of clinically and genetically heterogeneous retinal degenerative hereditary diseases that cause severe vision impairment […]

Protecting effects and mechanism of tert-butyl hydroquinone on retinal cells in type 2 diabetic rats

Authors: Han Peiyan,  Zhang Siyuan,  Li Jingyan,  Huang Qi,  Tian Min,  Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.06.004 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 496-502. Abstract                              [Download PDF] [Read Full Text] Background Apoptosis is a primary clinical pathological mechanism of diabetic retinopathy […]

Inhibitory effects of bevacizumab on filtering bleb scarring following trabeculectomy in rabbits

Authors: Liang Pei,  Yang Jin,  Lin Jinyong DOI: 10.3760/cma.j.issn.2095-0160.2016.07.004 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 591-596. Abstract                              [Download PDF] [Read Full Text] Background The primary reason to trabeculectomy failure is fibrosis of conjunctiva and episclera because of progressive fibroblast proliferation and collagen deposition […]

Establishment of chronic ocular hypertension rat model by transgoniscope laser photocoagulation to trabecular meshwork and its comparison with translimbal laser photocoagulation

Authors: Ma Di,  Huang Chukai,  Cen Lingping,  Zhang Mingzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.07.002 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 580-584. Abstract                              [Download PDF] [Read Full Text] Background The establishment of chronic ocular hypertension is a basis for the research of glaucoma.Previous laser photocoagulation method to […]